Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103690320> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2103690320 abstract "Introduction Periodic Leg movements (PLM) have been previously reported in spinal cord injury (SCI), but never analyzed thoroughly. The objective of this study was to investigate the association between PLM and cortical and autonomic arousals in a patient with a complete SCI. Also the effect of a dopamine agonist was evaluated. Materials and methods Characterization of the SCI was done following the “International Standards for Neurological Classification of Spinal Cord Injury” and by performing a cervical MRI. Two separate baseline sleep recordings were performed with tibialis anterior EMG. A third similar recording was carried out under dopamine agonist medication. Results The SCI was found motor and sensory complete, indicating an injury of ASIA A severity. The MRI finding supported the clinical assessment of complete injury. PLM indexes were 148.2/h and 36.4/ h in the baseline sleep studies. Leg movements were disconnected from cortical arousals, as well as from respiratory or heart rate events. Heart rate events were associated with respiratory cortical arousals. All leg movements were abolished by pramipexole. Conclusion The presence of PLM in a patient with a complete cervical SCI indicates that they may appear without a generator of the movements in the brain. The disconnection of PLM from cortical, respiratory or cardiac events also supports a spinal pacemaker or peripheral trigger mechanism. Suppression of movements during the dopaminergic intervention suggests that the site of action of pramipexole in our patient is either in the spinal cord or periphery. Our observations add significant knowledge to the current models of the genesis for PLM and warrant studies in larger populations. Acknowledgements Professor Juha Ohman and Dr. Eerika Koskinen from Department of Neurosciences and Rehabilitation, University of Tampere, are acknowledged for their valuable contribution to the study." @default.
- W2103690320 created "2016-06-24" @default.
- W2103690320 creator A5001080390 @default.
- W2103690320 creator A5011230186 @default.
- W2103690320 creator A5014114786 @default.
- W2103690320 creator A5077742615 @default.
- W2103690320 creator A5080542753 @default.
- W2103690320 creator A5088312472 @default.
- W2103690320 date "2013-12-01" @default.
- W2103690320 modified "2023-09-28" @default.
- W2103690320 title "Periodic leg movements in spinal cord injury: evaluation of arousals and treatment effect" @default.
- W2103690320 doi "https://doi.org/10.1016/j.sleep.2013.11.619" @default.
- W2103690320 hasPublicationYear "2013" @default.
- W2103690320 type Work @default.
- W2103690320 sameAs 2103690320 @default.
- W2103690320 citedByCount "0" @default.
- W2103690320 crossrefType "journal-article" @default.
- W2103690320 hasAuthorship W2103690320A5001080390 @default.
- W2103690320 hasAuthorship W2103690320A5011230186 @default.
- W2103690320 hasAuthorship W2103690320A5014114786 @default.
- W2103690320 hasAuthorship W2103690320A5077742615 @default.
- W2103690320 hasAuthorship W2103690320A5080542753 @default.
- W2103690320 hasAuthorship W2103690320A5088312472 @default.
- W2103690320 hasConcept C126322002 @default.
- W2103690320 hasConcept C137183658 @default.
- W2103690320 hasConcept C15744967 @default.
- W2103690320 hasConcept C169760540 @default.
- W2103690320 hasConcept C2778334475 @default.
- W2103690320 hasConcept C2779134260 @default.
- W2103690320 hasConcept C2779734285 @default.
- W2103690320 hasConcept C2779989193 @default.
- W2103690320 hasConcept C2780775167 @default.
- W2103690320 hasConcept C42219234 @default.
- W2103690320 hasConcept C513476851 @default.
- W2103690320 hasConcept C71924100 @default.
- W2103690320 hasConcept C99508421 @default.
- W2103690320 hasConceptScore W2103690320C126322002 @default.
- W2103690320 hasConceptScore W2103690320C137183658 @default.
- W2103690320 hasConceptScore W2103690320C15744967 @default.
- W2103690320 hasConceptScore W2103690320C169760540 @default.
- W2103690320 hasConceptScore W2103690320C2778334475 @default.
- W2103690320 hasConceptScore W2103690320C2779134260 @default.
- W2103690320 hasConceptScore W2103690320C2779734285 @default.
- W2103690320 hasConceptScore W2103690320C2779989193 @default.
- W2103690320 hasConceptScore W2103690320C2780775167 @default.
- W2103690320 hasConceptScore W2103690320C42219234 @default.
- W2103690320 hasConceptScore W2103690320C513476851 @default.
- W2103690320 hasConceptScore W2103690320C71924100 @default.
- W2103690320 hasConceptScore W2103690320C99508421 @default.
- W2103690320 hasLocation W21036903201 @default.
- W2103690320 hasOpenAccess W2103690320 @default.
- W2103690320 hasPrimaryLocation W21036903201 @default.
- W2103690320 hasRelatedWork W1994619814 @default.
- W2103690320 hasRelatedWork W2043258358 @default.
- W2103690320 hasRelatedWork W2075488102 @default.
- W2103690320 hasRelatedWork W2090808108 @default.
- W2103690320 hasRelatedWork W2161721665 @default.
- W2103690320 hasRelatedWork W2253786617 @default.
- W2103690320 hasRelatedWork W2334018636 @default.
- W2103690320 hasRelatedWork W2409997452 @default.
- W2103690320 hasRelatedWork W2412849684 @default.
- W2103690320 hasRelatedWork W2543160101 @default.
- W2103690320 hasRelatedWork W2760346705 @default.
- W2103690320 hasRelatedWork W2766893744 @default.
- W2103690320 hasRelatedWork W2767740376 @default.
- W2103690320 hasRelatedWork W2994665412 @default.
- W2103690320 hasRelatedWork W3015406589 @default.
- W2103690320 hasRelatedWork W3038498107 @default.
- W2103690320 hasRelatedWork W3120318981 @default.
- W2103690320 hasRelatedWork W3122518651 @default.
- W2103690320 hasRelatedWork W3208914573 @default.
- W2103690320 hasRelatedWork W2184843243 @default.
- W2103690320 isParatext "false" @default.
- W2103690320 isRetracted "false" @default.
- W2103690320 magId "2103690320" @default.
- W2103690320 workType "article" @default.