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- W2103698259 abstract "Abstract A very efficient enzymatic method was developed for the synthesis of cyclic γ‐lactam and γ‐amino acid enantiomers, intermediates for drugs with a prominent turnover (e.g., abacavir and carbovir), through the CAL‐B‐catalysed enantioselective ( E > 200) hydrolysis of the corresponding N ‐Boc protected and unprotected racemic γ‐lactams with H 2 O in i Pr 2 O. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)" @default.
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- W2103698259 date "2008-10-16" @default.
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- W2103698259 title "Enzymatic Method for the Synthesis of Blockbuster Drug Intermediates - Synthesis of Five-Membered Cyclic γ-Amino Acid and γ-Lactam Enantiomers" @default.
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- W2103698259 doi "https://doi.org/10.1002/ejoc.200800723" @default.
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