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- W2103702920 abstract "Diatoms are unicellular algae responsible for approximately 20% of global carbon fixation. Their evolution by secondary endocytobiosis resulted in a complex cellular structure and metabolism compared to algae with primary plastids. The sulfate assimilation and methionine synthesis pathways provide S-containing amino acids for the synthesis of proteins and a range of metabolites such as dimethylsulfoniopropionate. To obtain an insight into the localization and organization of the sulfur metabolism pathways we surveyed the genome of Thalassiosira pseudonana-a model organism for diatom research. We have identified and annotated genes for enzymes involved in respective pathways. Protein localization was predicted using similarities to known signal peptide motifs. We performed detailed phylogenetic analyses of enzymes involved in sulfate uptake/reduction and methionine metabolism. Moreover, we have found in up-stream sequences of studied diatoms methionine biosynthesis genes a conserved motif, which shows similarity to the Met31, a cis-motif regulating expression of methionine biosynthesis genes in yeast." @default.
- W2103702920 created "2016-06-24" @default.
- W2103702920 creator A5031140842 @default.
- W2103702920 creator A5060417288 @default.
- W2103702920 date "2015-08-04" @default.
- W2103702920 modified "2023-09-23" @default.
- W2103702920 title "Phylogenetic analysis of methionine synthesis genes from Thalassiosira pseudonana" @default.
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- W2103702920 doi "https://doi.org/10.1186/s40064-015-1163-8" @default.
- W2103702920 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4523565" @default.
- W2103702920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26251775" @default.
- W2103702920 hasPublicationYear "2015" @default.
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