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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103706757> ?p ?o ?g. }

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• W2103706757 abstract "ABSTRACT Chemokine receptor CXCR4 (also known as LESTR and fusin) has been shown to function as a coreceptor for T-cell-tropic strains of human immunodeficiency virus type 1 (HIV-1). We have developed a binding assay to show that HIV envelope (Env) can interact with CXCR4 independently of CD4 but that this binding is markedly enhanced by the previous interaction of Env with soluble CD4. We also show that nonglycosylated HIV-1 SF-2 gp120 or sodium metaperiodate-treated oligomeric gp160 from HIV-1 451 bound much more readily to CXCR4 than their counterparts with intact carbohydrate residues did." @default.
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• W2103706757 date "1998-03-01" @default.
• W2103706757 modified "2023-10-10" @default.
• W2103706757 title "Human Immunodeficiency Virus (HIV) Envelope Binds to CXCR4 Independently of CD4, and Binding Can Be Enhanced by Interaction with Soluble CD4 or by HIV Envelope Deglycosylation" @default.
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• W2103706757 doi "https://doi.org/10.1128/jvi.72.3.2500-2504.1998" @default.
• W2103706757 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/109552" @default.
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