FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103711473> ?p ?o ?g. }

• W2103711473 abstract "The leaves and roots of Cissampelos mucronata A. Rich (Menispermaceae) are widely used in the tropics and subtropics to manage various ailments such as gastro-intestinal complaints, menstrual problems, venereal diseases and malaria. In the Coast region, Tanzania, roots are used to treat wounds due to extraction of jigger. Leaves of Tephrosia villosa (L) Pers (Leguminosae) are reported to be used in the treatment of diabetes mellitus in India. In this study, extracts from the roots and aerial parts of C. mucronata and extracts from leaves, fruits, twigs and roots of T. villosa were evaluated for larvicidal activity, brine shrimps toxicity and antimicrobial activity. Powdered materials from C. mucronata were extracted sequentially by dichloromethane followed by ethanol while materials from T.villosa were extracted by ethanol only. The extracts obtained were evaluated for larvicidal activity using Culex quinquefasciatus Say larvae, cytotoxicity using brine shrimp larvae and antimicrobial activity using bacteria and fungi. Extracts from aerial parts of C. Mucronata exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholera, Bacillus anthracis, Streptococcus faecalis and antifungal activity against Candida albicans and Cryptococcus neoformans. They exhibited very low toxicity to brine shrimps and had no larvicidal activity. The root extracts exhibited good larvicidal activity but weak antimicrobial activity. The root dichloromethane extracts from C. mucronata was found to be more toxic with an LC50 value of 59.608 μg/mL while ethanolic extracts from root were not toxic with LC50>100 μg/mL). Ethanol extracts from fruits and roots of T. villosa were found to be very toxic with LC50 values of 9.690 μg/mL and 4.511 μg/mL, respectively, while, ethanol extracts from leaves and twigs of T. villosa were found to be non toxic (LC50>100 μg/mL). These results support the use of C. mucronata in traditional medicine for treatment of wounds. Extracts of C. mucronata have potential to yield active antimicrobial and larvicidal compounds. The high brine shrimp toxicity of T. villosa corroborates with literature reports that the plant is toxic to both livestock and fish. The results further suggest that T. villosa extracts have potential to yield larvicidal and possibly cytotoxic compounds. Further studies to investigate the bioactive compounds responsible for the observed biological effects are suggested." @default.
• W2103711473 created "2016-06-24" @default.
• W2103711473 creator A5003269172 @default.
• W2103711473 creator A5019953049 @default.
• W2103711473 creator A5021777188 @default.
• W2103711473 creator A5064621758 @default.
• W2103711473 creator A5065529422 @default.
• W2103711473 creator A5072423180 @default.
• W2103711473 creator A5090080222 @default.
• W2103711473 date "2011-04-23" @default.
• W2103711473 modified "2023-10-17" @default.
• W2103711473 title "Larvicidal, antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region, Tanzania" @default.
• W2103711473 cites W115705620 @default.
• W2103711473 cites W1612891045 @default.
• W2103711473 cites W1973793467 @default.
• W2103711473 cites W1973983227 @default.
• W2103711473 cites W1999067093 @default.
• W2103711473 cites W2015884448 @default.
• W2103711473 cites W2020670359 @default.
• W2103711473 cites W2037246614 @default.
• W2103711473 cites W2044543789 @default.
• W2103711473 cites W2047634271 @default.
• W2103711473 cites W2069710405 @default.
• W2103711473 cites W2070413755 @default.
• W2103711473 cites W2074509460 @default.
• W2103711473 cites W2124995963 @default.
• W2103711473 doi "https://doi.org/10.1186/1472-6882-11-33" @default.
• W2103711473 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3095574" @default.
• W2103711473 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21513544" @default.
• W2103711473 hasPublicationYear "2011" @default.
• W2103711473 type Work @default.
• W2103711473 sameAs 2103711473 @default.
• W2103711473 citedByCount "26" @default.
• W2103711473 countsByYear W21037114732012 @default.
• W2103711473 countsByYear W21037114732013 @default.
• W2103711473 countsByYear W21037114732014 @default.
• W2103711473 countsByYear W21037114732015 @default.
• W2103711473 countsByYear W21037114732016 @default.
• W2103711473 countsByYear W21037114732019 @default.
• W2103711473 countsByYear W21037114732020 @default.
• W2103711473 countsByYear W21037114732021 @default.
• W2103711473 countsByYear W21037114732022 @default.
• W2103711473 countsByYear W21037114732023 @default.
• W2103711473 crossrefType "journal-article" @default.
• W2103711473 hasAuthorship W2103711473A5003269172 @default.
• W2103711473 hasAuthorship W2103711473A5019953049 @default.
• W2103711473 hasAuthorship W2103711473A5021777188 @default.
• W2103711473 hasAuthorship W2103711473A5064621758 @default.
• W2103711473 hasAuthorship W2103711473A5065529422 @default.
• W2103711473 hasAuthorship W2103711473A5072423180 @default.
• W2103711473 hasAuthorship W2103711473A5090080222 @default.
• W2103711473 hasBestOaLocation W21037114731 @default.
• W2103711473 hasConcept C178790620 @default.
• W2103711473 hasConcept C185592680 @default.
• W2103711473 hasConcept C18903297 @default.
• W2103711473 hasConcept C2775873308 @default.
• W2103711473 hasConcept C2777912774 @default.
• W2103711473 hasConcept C2780096663 @default.
• W2103711473 hasConcept C2781201647 @default.
• W2103711473 hasConcept C29730261 @default.
• W2103711473 hasConcept C4937899 @default.
• W2103711473 hasConcept C556039675 @default.
• W2103711473 hasConcept C59822182 @default.
• W2103711473 hasConcept C68874143 @default.
• W2103711473 hasConcept C71924100 @default.
• W2103711473 hasConcept C86803240 @default.
• W2103711473 hasConcept C89423630 @default.
• W2103711473 hasConceptScore W2103711473C178790620 @default.
• W2103711473 hasConceptScore W2103711473C185592680 @default.
• W2103711473 hasConceptScore W2103711473C18903297 @default.
• W2103711473 hasConceptScore W2103711473C2775873308 @default.
• W2103711473 hasConceptScore W2103711473C2777912774 @default.
• W2103711473 hasConceptScore W2103711473C2780096663 @default.
• W2103711473 hasConceptScore W2103711473C2781201647 @default.
• W2103711473 hasConceptScore W2103711473C29730261 @default.
• W2103711473 hasConceptScore W2103711473C4937899 @default.
• W2103711473 hasConceptScore W2103711473C556039675 @default.
• W2103711473 hasConceptScore W2103711473C59822182 @default.
• W2103711473 hasConceptScore W2103711473C68874143 @default.
• W2103711473 hasConceptScore W2103711473C71924100 @default.
• W2103711473 hasConceptScore W2103711473C86803240 @default.
• W2103711473 hasConceptScore W2103711473C89423630 @default.
• W2103711473 hasIssue "1" @default.
• W2103711473 hasLocation W21037114731 @default.
• W2103711473 hasLocation W21037114732 @default.
• W2103711473 hasLocation W21037114733 @default.
• W2103711473 hasLocation W21037114734 @default.
• W2103711473 hasLocation W21037114735 @default.
• W2103711473 hasOpenAccess W2103711473 @default.
• W2103711473 hasPrimaryLocation W21037114731 @default.
• W2103711473 hasRelatedWork W2058141153 @default.
• W2103711473 hasRelatedWork W2133033644 @default.
• W2103711473 hasRelatedWork W2189192931 @default.
• W2103711473 hasRelatedWork W2299015985 @default.
• W2103711473 hasRelatedWork W2965512874 @default.
• W2103711473 hasRelatedWork W2993656866 @default.
• W2103711473 hasRelatedWork W3215510064 @default.
• W2103711473 hasRelatedWork W4292567115 @default.
• W2103711473 hasRelatedWork W603859946 @default.
• W2103711473 hasRelatedWork W2914151012 @default.

• next