Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103742481> ?p ?o ?g. }
- W2103742481 endingPage "627" @default.
- W2103742481 startingPage "619" @default.
- W2103742481 abstract "Abstract Meiotic recombination and DNA repair are mediated by overlapping sets of genes. In the yeast Saccharomyces cerevisiae, many genes required to repair DNA double-strand breaks are also required for meiotic recombination. In contrast, mutations in genes required for nucleotide excision repair (NER) have no detectable effects on meiotic recombination in S. cerevisiae. The Drosophila melanogaster mei-9 gene is unique among known recombination genes in that it is required for both meiotic recombination and NER. We have analyzed the mei-9 gene at the molecular level and found that it encodes a homologue of the S. cerevisiae excision repair protein Rad1, the probable homologue of mammalian XPF/ERCC4. Hence, the predominant process of meiotic recombination in Drosophila proceeds through a pathway that is at least partially distinct from that of S. cerevisiae, in that it requires an NER protein. The biochemical properties of the Rad1 protein allow us to explain the observation that mei-9 mutants suppress reciprocal exchange without suppressing the frequency of gene conversion." @default.
- W2103742481 created "2016-06-24" @default.
- W2103742481 creator A5020880841 @default.
- W2103742481 creator A5021108399 @default.
- W2103742481 creator A5043365967 @default.
- W2103742481 creator A5052983619 @default.
- W2103742481 date "1995-10-01" @default.
- W2103742481 modified "2023-09-23" @default.
- W2103742481 title "The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1." @default.
- W2103742481 cites W1866756245 @default.
- W2103742481 cites W1927076786 @default.
- W2103742481 cites W1933256326 @default.
- W2103742481 cites W1947674027 @default.
- W2103742481 cites W1956471488 @default.
- W2103742481 cites W1977918604 @default.
- W2103742481 cites W1980227683 @default.
- W2103742481 cites W1988875152 @default.
- W2103742481 cites W1999104040 @default.
- W2103742481 cites W2009310436 @default.
- W2103742481 cites W2016544300 @default.
- W2103742481 cites W2017201927 @default.
- W2103742481 cites W2024172421 @default.
- W2103742481 cites W2027074014 @default.
- W2103742481 cites W2027583726 @default.
- W2103742481 cites W2033918866 @default.
- W2103742481 cites W2034056708 @default.
- W2103742481 cites W2034252391 @default.
- W2103742481 cites W2034720562 @default.
- W2103742481 cites W2043284348 @default.
- W2103742481 cites W2047047608 @default.
- W2103742481 cites W2048906582 @default.
- W2103742481 cites W2050060181 @default.
- W2103742481 cites W2055043387 @default.
- W2103742481 cites W2069396761 @default.
- W2103742481 cites W2097475918 @default.
- W2103742481 cites W2104029140 @default.
- W2103742481 cites W2104290805 @default.
- W2103742481 cites W2114246483 @default.
- W2103742481 cites W2114968789 @default.
- W2103742481 cites W2119004240 @default.
- W2103742481 cites W2130394151 @default.
- W2103742481 cites W2130972387 @default.
- W2103742481 cites W2133114796 @default.
- W2103742481 cites W2140360876 @default.
- W2103742481 cites W2143210482 @default.
- W2103742481 cites W2148051437 @default.
- W2103742481 cites W2153286696 @default.
- W2103742481 cites W2166182249 @default.
- W2103742481 cites W2290020609 @default.
- W2103742481 cites W332945858 @default.
- W2103742481 cites W69783081 @default.
- W2103742481 doi "https://doi.org/10.1093/genetics/141.2.619" @default.
- W2103742481 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1206761" @default.
- W2103742481 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8647398" @default.
- W2103742481 hasPublicationYear "1995" @default.
- W2103742481 type Work @default.
- W2103742481 sameAs 2103742481 @default.
- W2103742481 citedByCount "160" @default.
- W2103742481 countsByYear W21037424812012 @default.
- W2103742481 countsByYear W21037424812013 @default.
- W2103742481 countsByYear W21037424812014 @default.
- W2103742481 countsByYear W21037424812015 @default.
- W2103742481 countsByYear W21037424812016 @default.
- W2103742481 countsByYear W21037424812017 @default.
- W2103742481 countsByYear W21037424812018 @default.
- W2103742481 countsByYear W21037424812019 @default.
- W2103742481 countsByYear W21037424812020 @default.
- W2103742481 countsByYear W21037424812021 @default.
- W2103742481 countsByYear W21037424812022 @default.
- W2103742481 crossrefType "journal-article" @default.
- W2103742481 hasAuthorship W2103742481A5020880841 @default.
- W2103742481 hasAuthorship W2103742481A5021108399 @default.
- W2103742481 hasAuthorship W2103742481A5043365967 @default.
- W2103742481 hasAuthorship W2103742481A5052983619 @default.
- W2103742481 hasBestOaLocation W21037424812 @default.
- W2103742481 hasConcept C101434241 @default.
- W2103742481 hasConcept C102744134 @default.
- W2103742481 hasConcept C104317684 @default.
- W2103742481 hasConcept C104451858 @default.
- W2103742481 hasConcept C112212490 @default.
- W2103742481 hasConcept C127764415 @default.
- W2103742481 hasConcept C134935766 @default.
- W2103742481 hasConcept C135300049 @default.
- W2103742481 hasConcept C143065580 @default.
- W2103742481 hasConcept C148196450 @default.
- W2103742481 hasConcept C156695909 @default.
- W2103742481 hasConcept C2777576037 @default.
- W2103742481 hasConcept C2780104201 @default.
- W2103742481 hasConcept C54355233 @default.
- W2103742481 hasConcept C86803240 @default.
- W2103742481 hasConceptScore W2103742481C101434241 @default.
- W2103742481 hasConceptScore W2103742481C102744134 @default.
- W2103742481 hasConceptScore W2103742481C104317684 @default.
- W2103742481 hasConceptScore W2103742481C104451858 @default.
- W2103742481 hasConceptScore W2103742481C112212490 @default.
- W2103742481 hasConceptScore W2103742481C127764415 @default.
- W2103742481 hasConceptScore W2103742481C134935766 @default.
- W2103742481 hasConceptScore W2103742481C135300049 @default.