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- W2103751457 abstract "Primary biliary cirrhosis is a chronic autoimmune inflammatory disease of the liver with a striking female preponderance. It has an insidious onset and typically affects middle-aged women. The disease manifests gradually with symptoms of fatigue, pruritis, and increased alkaline phosphatase levels on laboratory evaluation. The hallmark of the disease is the circulating antimitochondrial antibody. Histology is characterized by inflammation of the bile ducts, destruction of cholangiocytes, and subsequent cholestasis, progressing to biliary cirrhosis. The standard treatment for primary biliary cirrhosis is ursodeoxycholic acid, which improves survival, but the disease can still lead to cirrhosis and liver failure over decades." @default.
- W2103751457 created "2016-06-24" @default.
- W2103751457 creator A5043717181 @default.
- W2103751457 creator A5071991131 @default.
- W2103751457 creator A5073949691 @default.
- W2103751457 date "2011-06-01" @default.
- W2103751457 modified "2023-10-03" @default.
- W2103751457 title "Primary Biliary Cirrhosis" @default.
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- W2103751457 doi "https://doi.org/10.1016/j.gtc.2011.03.008" @default.
- W2103751457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21601785" @default.
- W2103751457 hasPublicationYear "2011" @default.
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