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• W2103754608 abstract "Previous research demonstrated a positive effect of d-amphetamine on long-term verbal memory. An improvement in memory for contextual information is proposed as a possible mechanism underlying the d-amphetamine facilitation effect.A double blind, placebo controlled experiment was used to examine the processes involved in episodic memory affected by an acute administration of d-amphetamine. We investigated whether positive effects of d-amphetamine on item memory could be extended to context information by using a source memory paradigm.In a within-subjects design with two sessions, two study lists were presented in each session and participants were required to make an old/new recognition decision (item memory) and a list discrimination judgement (source memory) after delays of 1 h, 1 day and 1 week.Enhancement of item memory after d-amphetamine intake was observed on delayed tests only, confirming that amphetamine does not affect short-term memory or memory acquisition, but rather a process operating after initial encoding. Importantly, we found an enhancement in remembering the source of recognized items after d-amphetamine administration.The present study suggests that an acute administration of d-amphetamine helps to bind different features of an item in memory, in turn leading to an increased ability to recollect both the item and its context." @default.
• W2103754608 created "2016-06-24" @default.
• W2103754608 creator A5024918261 @default.
• W2103754608 creator A5059575238 @default.
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• W2103754608 date "2010-06-01" @default.
• W2103754608 modified "2023-10-13" @default.
• W2103754608 title "Effect of an acute d-amphetamine administration on context information memory in healthy volunteers: evidence from a source memory task" @default.
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• W2103754608 doi "https://doi.org/10.1002/hup.1120" @default.
• W2103754608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20521323" @default.
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