Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103757921> ?p ?o ?g. }
- W2103757921 endingPage "1022" @default.
- W2103757921 startingPage "1011" @default.
- W2103757921 abstract "Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukaemia (ALL) is the most common subtype of ALL in adults. Conventional chemotherapy-based approaches that are effective in other precursor B cell ALL cases have a poor chances of cure in patients with a Ph+ diagnosis. Therefore, allogeneic stem cell transplantation performed during the first remission is the recommended therapy. Recently, the availability of imatinib mesylate and other tyrosine kinase inhibitors and small molecules that affect the BCR/ABL signalling pathways has introduced a new therapeutic opportunity, and could change the treatment paradigm and prognosis for these patients. In this article, the results from clinical trials using imatinib in relapsed/refractory patients and as front-line therapy are described. In addition, preliminary experiences with novel tyrosine kinase inhibitors in imatinib-resistant Ph+ ALL are discussed." @default.
- W2103757921 created "2016-06-24" @default.
- W2103757921 creator A5028913158 @default.
- W2103757921 creator A5037413392 @default.
- W2103757921 creator A5044224344 @default.
- W2103757921 creator A5073761054 @default.
- W2103757921 date "2006-09-21" @default.
- W2103757921 modified "2023-10-16" @default.
- W2103757921 title "Advances and potential treatment for Philadelphia chromosome-positive adult acute lymphoid leukaemia" @default.
- W2103757921 cites W1249635699 @default.
- W2103757921 cites W1558827591 @default.
- W2103757921 cites W1644813534 @default.
- W2103757921 cites W175560591 @default.
- W2103757921 cites W1862517694 @default.
- W2103757921 cites W1973720500 @default.
- W2103757921 cites W1984160018 @default.
- W2103757921 cites W1989860697 @default.
- W2103757921 cites W1994309500 @default.
- W2103757921 cites W2016086822 @default.
- W2103757921 cites W2019071187 @default.
- W2103757921 cites W2027139912 @default.
- W2103757921 cites W2037154482 @default.
- W2103757921 cites W2042794231 @default.
- W2103757921 cites W2043893054 @default.
- W2103757921 cites W2054251966 @default.
- W2103757921 cites W2065251641 @default.
- W2103757921 cites W2066998725 @default.
- W2103757921 cites W2070269177 @default.
- W2103757921 cites W2080380323 @default.
- W2103757921 cites W2084605742 @default.
- W2103757921 cites W2087562706 @default.
- W2103757921 cites W2092606584 @default.
- W2103757921 cites W2095443553 @default.
- W2103757921 cites W2097946794 @default.
- W2103757921 cites W2104073210 @default.
- W2103757921 cites W2106555552 @default.
- W2103757921 cites W2109292561 @default.
- W2103757921 cites W2109487699 @default.
- W2103757921 cites W2113703021 @default.
- W2103757921 cites W2116521328 @default.
- W2103757921 cites W2117730045 @default.
- W2103757921 cites W2120470347 @default.
- W2103757921 cites W2121484324 @default.
- W2103757921 cites W2124196948 @default.
- W2103757921 cites W2131067167 @default.
- W2103757921 cites W2137520438 @default.
- W2103757921 cites W2139499066 @default.
- W2103757921 cites W2150695629 @default.
- W2103757921 cites W2153701773 @default.
- W2103757921 cites W2158106590 @default.
- W2103757921 cites W2169401187 @default.
- W2103757921 cites W2312804644 @default.
- W2103757921 cites W2313760927 @default.
- W2103757921 cites W2316505355 @default.
- W2103757921 cites W2317034329 @default.
- W2103757921 cites W2549110367 @default.
- W2103757921 cites W2550859769 @default.
- W2103757921 cites W2569399182 @default.
- W2103757921 cites W2591552247 @default.
- W2103757921 doi "https://doi.org/10.1517/14712598.6.10.1011" @default.
- W2103757921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16989583" @default.
- W2103757921 hasPublicationYear "2006" @default.
- W2103757921 type Work @default.
- W2103757921 sameAs 2103757921 @default.
- W2103757921 citedByCount "10" @default.
- W2103757921 countsByYear W21037579212012 @default.
- W2103757921 countsByYear W21037579212015 @default.
- W2103757921 crossrefType "journal-article" @default.
- W2103757921 hasAuthorship W2103757921A5028913158 @default.
- W2103757921 hasAuthorship W2103757921A5037413392 @default.
- W2103757921 hasAuthorship W2103757921A5044224344 @default.
- W2103757921 hasAuthorship W2103757921A5073761054 @default.
- W2103757921 hasConcept C104317684 @default.
- W2103757921 hasConcept C121608353 @default.
- W2103757921 hasConcept C126322002 @default.
- W2103757921 hasConcept C138626823 @default.
- W2103757921 hasConcept C143998085 @default.
- W2103757921 hasConcept C170493617 @default.
- W2103757921 hasConcept C203014093 @default.
- W2103757921 hasConcept C2776694085 @default.
- W2103757921 hasConcept C2777583451 @default.
- W2103757921 hasConcept C2778729363 @default.
- W2103757921 hasConcept C2778820342 @default.
- W2103757921 hasConcept C2778904597 @default.
- W2103757921 hasConcept C28328180 @default.
- W2103757921 hasConcept C2911091166 @default.
- W2103757921 hasConcept C3019892230 @default.
- W2103757921 hasConcept C42362537 @default.
- W2103757921 hasConcept C502942594 @default.
- W2103757921 hasConcept C535046627 @default.
- W2103757921 hasConcept C54355233 @default.
- W2103757921 hasConcept C55493867 @default.
- W2103757921 hasConcept C71924100 @default.
- W2103757921 hasConcept C86803240 @default.
- W2103757921 hasConceptScore W2103757921C104317684 @default.
- W2103757921 hasConceptScore W2103757921C121608353 @default.
- W2103757921 hasConceptScore W2103757921C126322002 @default.
- W2103757921 hasConceptScore W2103757921C138626823 @default.