Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103758068> ?p ?o ?g. }
- W2103758068 endingPage "346" @default.
- W2103758068 startingPage "341" @default.
- W2103758068 abstract "Among the novel biologic therapeutics that will increase our ability to cure human cancer in the years to come, T cell therapy is one of the most promising approaches. However, with the possible exception of tumor-infiltrating lymphocytes therapy for melanoma, clinical trials of adoptive T-cell therapy for solid tumors have so far provided only clear proofs-of-principle to build on with further development. Epstein-Barr virus (EBV)-associated malignancies offer a unique model to develop T cell-based immune therapies, targeting viral antigens expressed on tumor cells. In the last two decades, EBV-specific cytotoxic T-lymphocytes (CTL) have been successfully employed for the prophylaxis and treatment of EBV-related lymphoproliferative disorders in immunocompromised hosts. More recently, this therapeutic approach has been applied to the setting of EBV-related solid tumors, such as nasopharyngeal carcinoma. The results are encouraging, although further improvements to the clinical protocols are clearly necessary to increase anti-tumor activity. Promising implementations are underway, including harnessing the therapeutic potential of CTLs specific for subdominant EBV latent cycle epitopes, and delineating strategies aimed at targeting immune evasion mechanisms exerted by tumor cells." @default.
- W2103758068 created "2016-06-24" @default.
- W2103758068 creator A5018500525 @default.
- W2103758068 creator A5038057110 @default.
- W2103758068 creator A5041464273 @default.
- W2103758068 creator A5042517744 @default.
- W2103758068 creator A5045484409 @default.
- W2103758068 creator A5047993250 @default.
- W2103758068 creator A5048660891 @default.
- W2103758068 creator A5050104358 @default.
- W2103758068 creator A5050682361 @default.
- W2103758068 creator A5065961744 @default.
- W2103758068 creator A5088425375 @default.
- W2103758068 creator A5091382573 @default.
- W2103758068 date "2011-01-01" @default.
- W2103758068 modified "2023-10-14" @default.
- W2103758068 title "T Cell Therapy for Nasopharyngeal Carcinoma" @default.
- W2103758068 cites W1556098051 @default.
- W2103758068 cites W1896113217 @default.
- W2103758068 cites W1965411116 @default.
- W2103758068 cites W1967445526 @default.
- W2103758068 cites W1968111108 @default.
- W2103758068 cites W1969762178 @default.
- W2103758068 cites W1973853361 @default.
- W2103758068 cites W1975615991 @default.
- W2103758068 cites W1978621251 @default.
- W2103758068 cites W1979936799 @default.
- W2103758068 cites W1983412131 @default.
- W2103758068 cites W1985981664 @default.
- W2103758068 cites W1993732758 @default.
- W2103758068 cites W2012068731 @default.
- W2103758068 cites W2015230607 @default.
- W2103758068 cites W2016671320 @default.
- W2103758068 cites W2020099065 @default.
- W2103758068 cites W2020920166 @default.
- W2103758068 cites W2022218275 @default.
- W2103758068 cites W2027723015 @default.
- W2103758068 cites W2036157741 @default.
- W2103758068 cites W2036495551 @default.
- W2103758068 cites W2041748431 @default.
- W2103758068 cites W2050293595 @default.
- W2103758068 cites W2059775855 @default.
- W2103758068 cites W2060007608 @default.
- W2103758068 cites W2064810566 @default.
- W2103758068 cites W2067490227 @default.
- W2103758068 cites W2079945341 @default.
- W2103758068 cites W2095617994 @default.
- W2103758068 cites W2095710861 @default.
- W2103758068 cites W2096689441 @default.
- W2103758068 cites W2096932117 @default.
- W2103758068 cites W2107252466 @default.
- W2103758068 cites W2107547219 @default.
- W2103758068 cites W2118745945 @default.
- W2103758068 cites W2123909678 @default.
- W2103758068 cites W2125919881 @default.
- W2103758068 cites W2127734125 @default.
- W2103758068 cites W2135208966 @default.
- W2103758068 cites W2135265711 @default.
- W2103758068 cites W2140048036 @default.
- W2103758068 cites W2140111836 @default.
- W2103758068 cites W2142047025 @default.
- W2103758068 cites W2143822310 @default.
- W2103758068 cites W2148523692 @default.
- W2103758068 cites W2153549003 @default.
- W2103758068 cites W2153641840 @default.
- W2103758068 cites W2159664205 @default.
- W2103758068 cites W2163510698 @default.
- W2103758068 cites W2222135509 @default.
- W2103758068 cites W2335365056 @default.
- W2103758068 cites W3022224433 @default.
- W2103758068 cites W64873609 @default.
- W2103758068 doi "https://doi.org/10.7150/jca.2.341" @default.
- W2103758068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3119400" @default.
- W2103758068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21716854" @default.
- W2103758068 hasPublicationYear "2011" @default.
- W2103758068 type Work @default.
- W2103758068 sameAs 2103758068 @default.
- W2103758068 citedByCount "26" @default.
- W2103758068 countsByYear W21037580682012 @default.
- W2103758068 countsByYear W21037580682013 @default.
- W2103758068 countsByYear W21037580682015 @default.
- W2103758068 countsByYear W21037580682016 @default.
- W2103758068 countsByYear W21037580682017 @default.
- W2103758068 countsByYear W21037580682018 @default.
- W2103758068 countsByYear W21037580682019 @default.
- W2103758068 countsByYear W21037580682020 @default.
- W2103758068 countsByYear W21037580682021 @default.
- W2103758068 countsByYear W21037580682022 @default.
- W2103758068 countsByYear W21037580682023 @default.
- W2103758068 crossrefType "journal-article" @default.
- W2103758068 hasAuthorship W2103758068A5018500525 @default.
- W2103758068 hasAuthorship W2103758068A5038057110 @default.
- W2103758068 hasAuthorship W2103758068A5041464273 @default.
- W2103758068 hasAuthorship W2103758068A5042517744 @default.
- W2103758068 hasAuthorship W2103758068A5045484409 @default.
- W2103758068 hasAuthorship W2103758068A5047993250 @default.
- W2103758068 hasAuthorship W2103758068A5048660891 @default.
- W2103758068 hasAuthorship W2103758068A5050104358 @default.