Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103758312> ?p ?o ?g. }
- W2103758312 endingPage "4583" @default.
- W2103758312 startingPage "4568" @default.
- W2103758312 abstract "Mitotic yeast (Saccharomyces cerevisiae) cells express five related septins (Cdc3, Cdc10, Cdc11, Cdc12, and Shs1) that form a cortical filamentous collar at the mother-bud neck necessary for normal morphogenesis and cytokinesis. All five possess an N-terminal GTPase domain and, except for Cdc10, a C-terminal extension (CTE) containing a predicted coiled coil. Here, we show that the CTEs of Cdc3 and Cdc12 are essential for their association and for the function of both septins in vivo. Cdc10 interacts with a Cdc3–Cdc12 complex independently of the CTE of either protein. In contrast to Cdc3 and Cdc12, the Cdc11 CTE, which recruits the nonessential septin Shs1, is dispensable for its function in vivo. In addition, Cdc11 forms a stoichiometric complex with Cdc12, independent of its CTE. Reconstitution of various multiseptin complexes and electron microscopic analysis reveal that Cdc3, Cdc11, and Cdc12 are all necessary and sufficient for septin filament formation, and presence of Cdc10 causes filament pairing. These data provide novel insights about the connectivity among the five individual septins in functional septin heteropentamers and the organization of septin filaments." @default.
- W2103758312 created "2016-06-24" @default.
- W2103758312 creator A5013931163 @default.
- W2103758312 creator A5015662191 @default.
- W2103758312 creator A5023385915 @default.
- W2103758312 creator A5026589340 @default.
- W2103758312 creator A5029415610 @default.
- W2103758312 creator A5032395126 @default.
- W2103758312 creator A5048920959 @default.
- W2103758312 creator A5070022547 @default.
- W2103758312 creator A5072934604 @default.
- W2103758312 date "2004-10-01" @default.
- W2103758312 modified "2023-10-17" @default.
- W2103758312 title "Protein–Protein Interactions Governing Septin Heteropentamer Assembly and Septin Filament Organization inSaccharomyces cerevisiae" @default.
- W2103758312 cites W1589290041 @default.
- W2103758312 cites W1965231243 @default.
- W2103758312 cites W1967390330 @default.
- W2103758312 cites W1970705112 @default.
- W2103758312 cites W1984746615 @default.
- W2103758312 cites W1991883398 @default.
- W2103758312 cites W1998377570 @default.
- W2103758312 cites W2009051079 @default.
- W2103758312 cites W2016491420 @default.
- W2103758312 cites W2016517861 @default.
- W2103758312 cites W2031483590 @default.
- W2103758312 cites W2055376777 @default.
- W2103758312 cites W2057764157 @default.
- W2103758312 cites W2063549537 @default.
- W2103758312 cites W2072803943 @default.
- W2103758312 cites W2075787930 @default.
- W2103758312 cites W2084121216 @default.
- W2103758312 cites W2098616171 @default.
- W2103758312 cites W2100057937 @default.
- W2103758312 cites W2105346492 @default.
- W2103758312 cites W2108148669 @default.
- W2103758312 cites W2117432787 @default.
- W2103758312 cites W2123825436 @default.
- W2103758312 cites W2125802531 @default.
- W2103758312 cites W2127398373 @default.
- W2103758312 cites W2129759722 @default.
- W2103758312 cites W2132417094 @default.
- W2103758312 cites W2138270253 @default.
- W2103758312 cites W2139609470 @default.
- W2103758312 cites W2141706916 @default.
- W2103758312 cites W2143145120 @default.
- W2103758312 cites W2146200179 @default.
- W2103758312 cites W2146503498 @default.
- W2103758312 cites W2146632337 @default.
- W2103758312 cites W2147143173 @default.
- W2103758312 cites W2148146668 @default.
- W2103758312 cites W2148175003 @default.
- W2103758312 cites W2148821974 @default.
- W2103758312 cites W2151025332 @default.
- W2103758312 cites W2160617617 @default.
- W2103758312 cites W2169333620 @default.
- W2103758312 cites W4243411621 @default.
- W2103758312 doi "https://doi.org/10.1091/mbc.e04-04-0330" @default.
- W2103758312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/519150" @default.
- W2103758312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15282341" @default.
- W2103758312 hasPublicationYear "2004" @default.
- W2103758312 type Work @default.
- W2103758312 sameAs 2103758312 @default.
- W2103758312 citedByCount "149" @default.
- W2103758312 countsByYear W21037583122012 @default.
- W2103758312 countsByYear W21037583122013 @default.
- W2103758312 countsByYear W21037583122014 @default.
- W2103758312 countsByYear W21037583122015 @default.
- W2103758312 countsByYear W21037583122016 @default.
- W2103758312 countsByYear W21037583122017 @default.
- W2103758312 countsByYear W21037583122018 @default.
- W2103758312 countsByYear W21037583122019 @default.
- W2103758312 countsByYear W21037583122020 @default.
- W2103758312 countsByYear W21037583122021 @default.
- W2103758312 countsByYear W21037583122022 @default.
- W2103758312 countsByYear W21037583122023 @default.
- W2103758312 crossrefType "journal-article" @default.
- W2103758312 hasAuthorship W2103758312A5013931163 @default.
- W2103758312 hasAuthorship W2103758312A5015662191 @default.
- W2103758312 hasAuthorship W2103758312A5023385915 @default.
- W2103758312 hasAuthorship W2103758312A5026589340 @default.
- W2103758312 hasAuthorship W2103758312A5029415610 @default.
- W2103758312 hasAuthorship W2103758312A5032395126 @default.
- W2103758312 hasAuthorship W2103758312A5048920959 @default.
- W2103758312 hasAuthorship W2103758312A5070022547 @default.
- W2103758312 hasAuthorship W2103758312A5072934604 @default.
- W2103758312 hasBestOaLocation W21037583122 @default.
- W2103758312 hasConcept C104317684 @default.
- W2103758312 hasConcept C1491633281 @default.
- W2103758312 hasConcept C179411191 @default.
- W2103758312 hasConcept C2777576037 @default.
- W2103758312 hasConcept C2779222958 @default.
- W2103758312 hasConcept C2911011838 @default.
- W2103758312 hasConcept C29537977 @default.
- W2103758312 hasConcept C45472230 @default.
- W2103758312 hasConcept C54355233 @default.
- W2103758312 hasConcept C85813293 @default.
- W2103758312 hasConcept C86803240 @default.
- W2103758312 hasConcept C95444343 @default.