FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103800577> ?p ?o ?g. }

• W2103800577 endingPage "344" @default.
• W2103800577 startingPage "337" @default.
• W2103800577 abstract "PURPOSE: To describe cortical hyperintensities in proton density-weighted images in six patients with presumed cyclosporine-induced neurotoxicity. METHODS: In six patients with clinical evidence of cyclosporine-related encephalopathy, MR imaging was performed after the onset of symptoms and signs (mean, 24 days after liver transplantation). Five of these patients had serial MR imaging for a period that varied from 2 to 20 months. Along with the imaging studies, the patients' clinical status was evaluated and various laboratory parameters, including blood pressure and levels of cyclosporine, cholesterol, and magnesium, were monitored. RESULTS: In all six patients, initial MR studies showed hyperintensity of several cerebral gyri that was unequivocal only on proton density-weighted images. Although in five patients these signal abnormalities were limited to the cortex, one patient had increased signal in the subjacent white matter as well. In one patient, the images were also remarkable for areas of cortical hyperintensities on T1-weighted images. In another patient, cortical enhancement occurred after administration of gadopentetate dimeglumine, with a normal cortical signal on the precontrast images. The abnormal cortical signal began to fade after cyclosporine reduction, but in two patients it remained visible for at least 20 months. The neurologic symptomatology associated with cyclosporine-induced neurotoxicity included seizures (three patients), speech disorder (three patients), and disturbance of consciousness (three patients). CONCLUSION: Cyclosporine-induced neurotoxicity occurring in patients after liver transplantation appears to affect the cerebral cortex preferentially. Because its MR equivalent resembles changes resulting from hypoxic injury or cortically centered vasculitis, we suspect the underlying mechanism may be a vascular injury that results in cortical hypoperfusion." @default.
• W2103800577 created "2016-06-24" @default.
• W2103800577 creator A5021512666 @default.
• W2103800577 creator A5023250412 @default.
• W2103800577 creator A5041277234 @default.
• W2103800577 creator A5086259808 @default.
• W2103800577 date "1996-02-01" @default.
• W2103800577 modified "2023-09-26" @default.
• W2103800577 title "Cortical hyperintensity on proton density-weighted images: An MR sign of cyclosporine-related encephalopathy." @default.
• W2103800577 cites W1964348247 @default.
• W2103800577 cites W1967205967 @default.
• W2103800577 cites W1990016536 @default.
• W2103800577 cites W1996466671 @default.
• W2103800577 cites W2002562482 @default.
• W2103800577 cites W2007152616 @default.
• W2103800577 cites W2014760345 @default.
• W2103800577 cites W2028393953 @default.
• W2103800577 cites W2036877142 @default.
• W2103800577 cites W2038186406 @default.
• W2103800577 cites W2053714857 @default.
• W2103800577 cites W2063797137 @default.
• W2103800577 cites W2070847681 @default.
• W2103800577 cites W2083113386 @default.
• W2103800577 cites W2094178424 @default.
• W2103800577 cites W2112679836 @default.
• W2103800577 cites W2125407940 @default.
• W2103800577 cites W2146026221 @default.
• W2103800577 cites W2150423833 @default.
• W2103800577 cites W2154349480 @default.
• W2103800577 cites W2333740086 @default.
• W2103800577 cites W2404323983 @default.
• W2103800577 cites W2409951642 @default.
• W2103800577 cites W2411430673 @default.
• W2103800577 cites W2481253611 @default.
• W2103800577 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8338360" @default.
• W2103800577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8938308" @default.
• W2103800577 hasPublicationYear "1996" @default.
• W2103800577 type Work @default.
• W2103800577 sameAs 2103800577 @default.
• W2103800577 citedByCount "24" @default.
• W2103800577 countsByYear W21038005772012 @default.
• W2103800577 countsByYear W21038005772016 @default.
• W2103800577 crossrefType "journal-article" @default.
• W2103800577 hasAuthorship W2103800577A5021512666 @default.
• W2103800577 hasAuthorship W2103800577A5023250412 @default.
• W2103800577 hasAuthorship W2103800577A5041277234 @default.
• W2103800577 hasAuthorship W2103800577A5086259808 @default.
• W2103800577 hasConcept C126322002 @default.
• W2103800577 hasConcept C126838900 @default.
• W2103800577 hasConcept C142724271 @default.
• W2103800577 hasConcept C143409427 @default.
• W2103800577 hasConcept C146638467 @default.
• W2103800577 hasConcept C2778621155 @default.
• W2103800577 hasConcept C2779281540 @default.
• W2103800577 hasConcept C2781041448 @default.
• W2103800577 hasConcept C2781192897 @default.
• W2103800577 hasConcept C2911091166 @default.
• W2103800577 hasConcept C2989005 @default.
• W2103800577 hasConcept C71924100 @default.
• W2103800577 hasConceptScore W2103800577C126322002 @default.
• W2103800577 hasConceptScore W2103800577C126838900 @default.
• W2103800577 hasConceptScore W2103800577C142724271 @default.
• W2103800577 hasConceptScore W2103800577C143409427 @default.
• W2103800577 hasConceptScore W2103800577C146638467 @default.
• W2103800577 hasConceptScore W2103800577C2778621155 @default.
• W2103800577 hasConceptScore W2103800577C2779281540 @default.
• W2103800577 hasConceptScore W2103800577C2781041448 @default.
• W2103800577 hasConceptScore W2103800577C2781192897 @default.
• W2103800577 hasConceptScore W2103800577C2911091166 @default.
• W2103800577 hasConceptScore W2103800577C2989005 @default.
• W2103800577 hasConceptScore W2103800577C71924100 @default.
• W2103800577 hasIssue "2" @default.
• W2103800577 hasLocation W21038005771 @default.
• W2103800577 hasOpenAccess W2103800577 @default.
• W2103800577 hasPrimaryLocation W21038005771 @default.
• W2103800577 hasRelatedWork W1873750670 @default.
• W2103800577 hasRelatedWork W1964348247 @default.
• W2103800577 hasRelatedWork W1975759226 @default.
• W2103800577 hasRelatedWork W1990379097 @default.
• W2103800577 hasRelatedWork W1997271863 @default.
• W2103800577 hasRelatedWork W2007335987 @default.
• W2103800577 hasRelatedWork W2011017461 @default.
• W2103800577 hasRelatedWork W2014025142 @default.
• W2103800577 hasRelatedWork W2014760345 @default.
• W2103800577 hasRelatedWork W2021980041 @default.
• W2103800577 hasRelatedWork W2067111489 @default.
• W2103800577 hasRelatedWork W2081029431 @default.
• W2103800577 hasRelatedWork W2103923888 @default.
• W2103800577 hasRelatedWork W2138825040 @default.
• W2103800577 hasRelatedWork W2150423833 @default.
• W2103800577 hasRelatedWork W2182631734 @default.
• W2103800577 hasRelatedWork W2187510501 @default.
• W2103800577 hasRelatedWork W2326297993 @default.
• W2103800577 hasRelatedWork W2333740086 @default.
• W2103800577 hasRelatedWork W42595324 @default.
• W2103800577 hasVolume "17" @default.
• W2103800577 isParatext "false" @default.
• W2103800577 isRetracted "false" @default.

• next