FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103802045> ?p ?o ?g. }

• W2103802045 endingPage "25" @default.
• W2103802045 startingPage "25" @default.
• W2103802045 abstract "Experiencing emotions engages high-order orbitofrontal and medial prefrontal areas, and expressing emotions involves low-level autonomic structures and peripheral organs. How is information from the cortex transmitted to the periphery? We used two parallel approaches to map simultaneously multiple pathways to determine if hypothalamic autonomic centres are a key link for orbitofrontal areas and medial prefrontal areas, which have been associated with emotional processes, as well as low-level spinal and brainstem autonomic structures. The latter innervate peripheral autonomic organs, whose activity is markedly increased during emotional arousal.We first determined if pathways linking the orbitofrontal cortex with the hypothalamus overlapped with projection neurons directed to the intermediolateral column of the spinal cord, with the aid of neural tracers injected in these disparate structures. We found that axons from orbitofrontal and medial prefrontal cortices converged in the hypothalamus with neurons projecting to brainstem and spinal autonomic centers, linking the highest with the lowest levels of the neuraxis. Using a parallel approach, we injected bidirectional tracers in the lateral hypothalamic area, an autonomic center, to label simultaneously cortical pathways leading to the hypothalamus, as well as hypothalamic axons projecting to low-level brainstem and spinal autonomic centers. We found densely distributed projection neurons in medial prefrontal and orbitofrontal cortices leading to the hypothalamus, as well as hypothalamic axonal terminations in several brainstem structures and the intermediolateral column of the spinal cord, which innervate peripheral autonomic organs. We then provided direct evidence that axons from medial prefrontal cortex synapse with hypothalamic neurons, terminating as large boutons, comparable in size to the highly efficient thalamocortical system. The interlinked orbitofrontal, medial prefrontal areas and hypothalamic autonomic centers were also connected with the amygdala.Descending pathways from orbitofrontal and medial prefrontal cortices, which are also linked with the amygdala, provide the means for speedy influence of the prefrontal cortex on the autonomic system, in processes underlying appreciation and expression of emotions." @default.
• W2103802045 created "2016-06-24" @default.
• W2103802045 creator A5002817479 @default.
• W2103802045 creator A5014167212 @default.
• W2103802045 creator A5019081971 @default.
• W2103802045 creator A5068883383 @default.
• W2103802045 date "2003-01-01" @default.
• W2103802045 modified "2023-10-14" @default.
• W2103802045 cites W1508054049 @default.
• W2103802045 cites W1562703792 @default.
• W2103802045 cites W1566047568 @default.
• W2103802045 cites W1582850395 @default.
• W2103802045 cites W1604943474 @default.
• W2103802045 cites W1605645356 @default.
• W2103802045 cites W1627229807 @default.
• W2103802045 cites W1796200935 @default.
• W2103802045 cites W1967880030 @default.
• W2103802045 cites W1969303073 @default.
• W2103802045 cites W1972251813 @default.
• W2103802045 cites W1975201511 @default.
• W2103802045 cites W1977122833 @default.
• W2103802045 cites W1985728804 @default.
• W2103802045 cites W1991911963 @default.
• W2103802045 cites W1993506310 @default.
• W2103802045 cites W1993891869 @default.
• W2103802045 cites W1993924263 @default.
• W2103802045 cites W1994008515 @default.
• W2103802045 cites W2002614006 @default.
• W2103802045 cites W2003169826 @default.
• W2103802045 cites W2010589854 @default.
• W2103802045 cites W2012483271 @default.
• W2103802045 cites W2015029893 @default.
• W2103802045 cites W2022462550 @default.
• W2103802045 cites W2023426544 @default.
• W2103802045 cites W2027570313 @default.
• W2103802045 cites W2032641816 @default.
• W2103802045 cites W2033020059 @default.
• W2103802045 cites W2035433235 @default.
• W2103802045 cites W2043917754 @default.
• W2103802045 cites W2044150847 @default.
• W2103802045 cites W2044337759 @default.
• W2103802045 cites W2054843294 @default.
• W2103802045 cites W2060622201 @default.
• W2103802045 cites W2062990061 @default.
• W2103802045 cites W2063535919 @default.
• W2103802045 cites W2066144672 @default.
• W2103802045 cites W2066923652 @default.
• W2103802045 cites W2071054798 @default.
• W2103802045 cites W2072484079 @default.
• W2103802045 cites W2078069011 @default.
• W2103802045 cites W2083227438 @default.
• W2103802045 cites W2084921574 @default.
• W2103802045 cites W2093365905 @default.
• W2103802045 cites W2099180447 @default.
• W2103802045 cites W2105809102 @default.
• W2103802045 cites W2111712154 @default.
• W2103802045 cites W2128312680 @default.
• W2103802045 cites W2138728119 @default.
• W2103802045 cites W2144463055 @default.
• W2103802045 cites W2147324517 @default.
• W2103802045 cites W2152416379 @default.
• W2103802045 cites W2158553737 @default.
• W2103802045 cites W2164058388 @default.
• W2103802045 cites W2604898199 @default.
• W2103802045 cites W329535511 @default.
• W2103802045 doi "https://doi.org/10.1186/1471-2202-4-25" @default.
• W2103802045 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/270042" @default.
• W2103802045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14536022" @default.
• W2103802045 hasPublicationYear "2003" @default.
• W2103802045 type Work @default.
• W2103802045 sameAs 2103802045 @default.
• W2103802045 citedByCount "302" @default.
• W2103802045 countsByYear W21038020452012 @default.
• W2103802045 countsByYear W21038020452013 @default.
• W2103802045 countsByYear W21038020452014 @default.
• W2103802045 countsByYear W21038020452015 @default.
• W2103802045 countsByYear W21038020452016 @default.
• W2103802045 countsByYear W21038020452017 @default.
• W2103802045 countsByYear W21038020452018 @default.
• W2103802045 countsByYear W21038020452019 @default.
• W2103802045 countsByYear W21038020452020 @default.
• W2103802045 countsByYear W21038020452021 @default.
• W2103802045 countsByYear W21038020452022 @default.
• W2103802045 countsByYear W21038020452023 @default.
• W2103802045 crossrefType "journal-article" @default.
• W2103802045 hasAuthorship W2103802045A5002817479 @default.
• W2103802045 hasAuthorship W2103802045A5014167212 @default.
• W2103802045 hasAuthorship W2103802045A5019081971 @default.
• W2103802045 hasAuthorship W2103802045A5068883383 @default.
• W2103802045 hasBestOaLocation W21038020451 @default.
• W2103802045 hasConcept C105702510 @default.
• W2103802045 hasConcept C15744967 @default.
• W2103802045 hasConcept C169760540 @default.
• W2103802045 hasConcept C169900460 @default.
• W2103802045 hasConcept C2776559556 @default.
• W2103802045 hasConcept C2777003273 @default.
• W2103802045 hasConcept C2780775167 @default.
• W2103802045 hasConcept C2781195155 @default.

• next