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- W2103872295 abstract "BackgroundBortezomib is a proteasome inhibitor currently studied in clinical trials of childhood cancers. So far, no side effects on bone growth have been reported in treated children. However, bortezomib was recently found to induce apoptosis in growth plate chondrocytes and impair linear bone growth in treated mice. We hypothesize that [Gly14]-humanin (HNG), a 24-amino acid synthetic antiapoptotic peptide, can prevent bortezomib-induced bone growth impairment." @default.
- W2103872295 created "2016-06-24" @default.
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- W2103872295 date "2014-03-01" @default.
- W2103872295 modified "2023-10-18" @default.
- W2103872295 title "Protective Role of Humanin on Bortezomib-Induced Bone Growth Impairment in Anticancer Treatment" @default.
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- W2103872295 doi "https://doi.org/10.1093/jnci/djt459" @default.
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