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- W21039335 abstract "Technological advances in medicine often precede parallel advances in knowledge. Such is the fundamental problem with the early detection and screening for prostate cancer. Until the mid-to late 1980s, rarely was prostate cancer screening an issue. Prior to this time, the only method to diagnose prostate cancer was to use digital rectal examination (DRE)—a test of some specificity but very poor sensitivity. Indeed, we previously found that many a patient who ultimately died of prostate cancer never was found to have an abnormal rectal examination (1). With DRE used as the only method of early diagnosis, as many as 30–35% of men diagnosed were found to have frank bony metastases, as many as 45–50% were found to have nodal disease, and only about one-third of men with clinically organ-confined disease were proved to have pathologically organ-confined disease at the time of radical prostatectomy (2,3). With tumors detected at such a late stage (many of the patients being incurable), little hubbub was raised over efforts to detect the disease at an earlier stage." @default.
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- W21039335 date "2001-01-01" @default.
- W21039335 modified "2023-09-23" @default.
- W21039335 title "Evidence of the Effectiveness of Prostate Cancer Screening" @default.
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- W21039335 doi "https://doi.org/10.1007/978-1-59259-099-5_11" @default.
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