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• W2103947312 abstract "Mitochondrial dysfunction is part of many pathological states in patients, such as sepsis or stroke. Presently, the monitoring of mitochondrial function in patients is extremely rare, even though NADH redox state is routinely measured in experimental animals. In this article, we describe the scientific backgrounds and practical use of mitochondrial NADH fluorescence measurement that was applied to patients in the past few years. In addition to NADH, we optically measured the microcirculatory blood flow and volume, as well as HbO(2) oxygenation, from the same tissue area. The four detected parameters provide real time data on tissue viability, which is critical for patients monitoring." @default.
• W2103947312 created "2016-06-24" @default.
• W2103947312 creator A5005680629 @default.
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• W2103947312 date "2007-09-01" @default.
• W2103947312 modified "2023-10-13" @default.
• W2103947312 title "Oxidation–reduction states of NADH in vivo: From animals to clinical use" @default.
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• W2103947312 doi "https://doi.org/10.1016/j.mito.2007.05.001" @default.
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