FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103973229> ?p ?o ?g. }

• W2103973229 endingPage "695" @default.
• W2103973229 startingPage "689" @default.
• W2103973229 abstract "Incubation of methoxypsoralen (5-MOP) in the presence of diploid yeast cells (Saccharomyces cerevisiae) before UV-A exposure leads to an incubation-time dependent decrease of photoinduced genotoxic effects. The reduction in photoinduced genotoxicity is stronger in cells grown in the presence of 20% glucose and containing high levels of cytochrome P-450 than in cells grown in the presence of 0.5% glucose and containing undetectable levels of cytochrome P-450. Inhibition of P-450 activity by specific inhibitors, such as tetrahydrofuran and metyrapone, strongly affects the observed decrease in 5-MOP genotoxicity, indicating the involvement of P-450 in 5-MOP metabolism. As demonstrated by spectrophotometric and chromatographic (HPLC) analysis during incubation of 5-MOP with P-450 containing yeast cells, 5-MOP gradually disappears from the cell supernatant of the incubation mixture. The reduction in the chromatographic peak corresponding to 5-MOP is accompanied by the appearance of a new peak that probably corresponds to a metabolite. As shown by the use of P-450 specific inhibitors, the metabolite appears to be due to P-450 mediated 5-MOP metabolisation. Its UV absorption spectrum suggests an alteration of the pyrone moiety of the 5-MOP molecule." @default.
• W2103973229 created "2016-06-24" @default.
• W2103973229 creator A5015296401 @default.
• W2103973229 creator A5015971858 @default.
• W2103973229 creator A5039621042 @default.
• W2103973229 creator A5079101633 @default.
• W2103973229 creator A5081932580 @default.
• W2103973229 creator A5085129994 @default.
• W2103973229 creator A5085146718 @default.
• W2103973229 date "1991-11-01" @default.
• W2103973229 modified "2023-10-18" @default.
• W2103973229 title "METABOLISM OF 5-METHOXYPSORALEN BY Saccharomyces cerevisiae" @default.
• W2103973229 cites W1775749144 @default.
• W2103973229 cites W1951469402 @default.
• W2103973229 cites W1968158918 @default.
• W2103973229 cites W1974125776 @default.
• W2103973229 cites W1982465731 @default.
• W2103973229 cites W1986893323 @default.
• W2103973229 cites W1998428458 @default.
• W2103973229 cites W2007040377 @default.
• W2103973229 cites W2015754855 @default.
• W2103973229 cites W2017354203 @default.
• W2103973229 cites W2017907476 @default.
• W2103973229 cites W2023284039 @default.
• W2103973229 cites W2046814558 @default.
• W2103973229 cites W2050907967 @default.
• W2103973229 cites W2055183514 @default.
• W2103973229 cites W2063676987 @default.
• W2103973229 cites W2074041231 @default.
• W2103973229 cites W2080876747 @default.
• W2103973229 cites W2139499014 @default.
• W2103973229 cites W2325956607 @default.
• W2103973229 cites W2443615604 @default.
• W2103973229 cites W27976059 @default.
• W2103973229 cites W4231490673 @default.
• W2103973229 cites W89095256 @default.
• W2103973229 cites W974598347 @default.
• W2103973229 doi "https://doi.org/10.1111/j.1751-1097.1991.tb02076.x" @default.
• W2103973229 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1798745" @default.
• W2103973229 hasPublicationYear "1991" @default.
• W2103973229 type Work @default.
• W2103973229 sameAs 2103973229 @default.
• W2103973229 citedByCount "4" @default.
• W2103973229 countsByYear W21039732292019 @default.
• W2103973229 crossrefType "journal-article" @default.
• W2103973229 hasAuthorship W2103973229A5015296401 @default.
• W2103973229 hasAuthorship W2103973229A5015971858 @default.
• W2103973229 hasAuthorship W2103973229A5039621042 @default.
• W2103973229 hasAuthorship W2103973229A5079101633 @default.
• W2103973229 hasAuthorship W2103973229A5081932580 @default.
• W2103973229 hasAuthorship W2103973229A5085129994 @default.
• W2103973229 hasAuthorship W2103973229A5085146718 @default.
• W2103973229 hasConcept C114246631 @default.
• W2103973229 hasConcept C178790620 @default.
• W2103973229 hasConcept C181199279 @default.
• W2103973229 hasConcept C185592680 @default.
• W2103973229 hasConcept C203014093 @default.
• W2103973229 hasConcept C25642318 @default.
• W2103973229 hasConcept C2776639595 @default.
• W2103973229 hasConcept C2777477808 @default.
• W2103973229 hasConcept C2777576037 @default.
• W2103973229 hasConcept C2778959862 @default.
• W2103973229 hasConcept C2779175014 @default.
• W2103973229 hasConcept C2779222958 @default.
• W2103973229 hasConcept C2780564577 @default.
• W2103973229 hasConcept C2780768313 @default.
• W2103973229 hasConcept C29730261 @default.
• W2103973229 hasConcept C55493867 @default.
• W2103973229 hasConcept C62231903 @default.
• W2103973229 hasConcept C86803240 @default.
• W2103973229 hasConceptScore W2103973229C114246631 @default.
• W2103973229 hasConceptScore W2103973229C178790620 @default.
• W2103973229 hasConceptScore W2103973229C181199279 @default.
• W2103973229 hasConceptScore W2103973229C185592680 @default.
• W2103973229 hasConceptScore W2103973229C203014093 @default.
• W2103973229 hasConceptScore W2103973229C25642318 @default.
• W2103973229 hasConceptScore W2103973229C2776639595 @default.
• W2103973229 hasConceptScore W2103973229C2777477808 @default.
• W2103973229 hasConceptScore W2103973229C2777576037 @default.
• W2103973229 hasConceptScore W2103973229C2778959862 @default.
• W2103973229 hasConceptScore W2103973229C2779175014 @default.
• W2103973229 hasConceptScore W2103973229C2779222958 @default.
• W2103973229 hasConceptScore W2103973229C2780564577 @default.
• W2103973229 hasConceptScore W2103973229C2780768313 @default.
• W2103973229 hasConceptScore W2103973229C29730261 @default.
• W2103973229 hasConceptScore W2103973229C55493867 @default.
• W2103973229 hasConceptScore W2103973229C62231903 @default.
• W2103973229 hasConceptScore W2103973229C86803240 @default.
• W2103973229 hasIssue "5" @default.
• W2103973229 hasLocation W21039732291 @default.
• W2103973229 hasLocation W21039732292 @default.
• W2103973229 hasOpenAccess W2103973229 @default.
• W2103973229 hasPrimaryLocation W21039732291 @default.
• W2103973229 hasRelatedWork W1992118424 @default.
• W2103973229 hasRelatedWork W2000875020 @default.
• W2103973229 hasRelatedWork W2008369582 @default.
• W2103973229 hasRelatedWork W2043426707 @default.
• W2103973229 hasRelatedWork W2056321983 @default.

• next