Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104007922> ?p ?o ?g. }
- W2104007922 endingPage "433" @default.
- W2104007922 startingPage "425" @default.
- W2104007922 abstract "Variation in the gene encoding for the norepinephrine transporter (NET, SLC6A2) has repeatedly been linked with ADHD, although there is some inconsistency regarding the association with specific genes. The variants for which most consistent association has been found are the NET variants rs3785157 and rs28386840. Here, we tested for their association with ADHD diagnosis and ADHD-related phenotypes during development in a longitudinal German community sample. Children were followed from age 4 to age 15, using diagnostic interviews to assess ADHD. Between the ages of 8 and 15 years, the Child Behavior Checklist (CBCL) was administered to the primary caregivers. The continuous performance task (CPT) was performed at age 15. Controlling for possible confounders, we found that homozygous carriers of the major A allele of the functional promoter variant rs28386840 displayed a higher rate of ADHD lifetime diagnosis. Moreover, homozygous carriers of the minor T allele of rs3785157 were more likely to develop ADHD and showed higher scores on the CBCL externalizing behavior scales. Additionally, we found that individuals heterozygous for rs3785157 made fewer omission errors in the CPT than homozygotes. This is the first longitudinal study to report associations between specific NET variants and ADHD-related phenotypes during the course of development." @default.
- W2104007922 created "2016-06-24" @default.
- W2104007922 creator A5015587903 @default.
- W2104007922 creator A5016008616 @default.
- W2104007922 creator A5024904538 @default.
- W2104007922 creator A5027904065 @default.
- W2104007922 creator A5036563678 @default.
- W2104007922 creator A5037267643 @default.
- W2104007922 creator A5039272292 @default.
- W2104007922 creator A5051201293 @default.
- W2104007922 creator A5072979590 @default.
- W2104007922 creator A5088638402 @default.
- W2104007922 date "2015-04-01" @default.
- W2104007922 modified "2023-10-01" @default.
- W2104007922 title "Association of norepinephrine transporter (NET, SLC6A2) genotype with ADHD-related phenotypes: Findings of a longitudinal study from birth to adolescence" @default.
- W2104007922 cites W1232286304 @default.
- W2104007922 cites W1964309132 @default.
- W2104007922 cites W1968016781 @default.
- W2104007922 cites W1968864839 @default.
- W2104007922 cites W1979677035 @default.
- W2104007922 cites W1981830992 @default.
- W2104007922 cites W1982047175 @default.
- W2104007922 cites W1983427473 @default.
- W2104007922 cites W1984551285 @default.
- W2104007922 cites W1987100645 @default.
- W2104007922 cites W1988693352 @default.
- W2104007922 cites W1991162436 @default.
- W2104007922 cites W1991772183 @default.
- W2104007922 cites W1992818547 @default.
- W2104007922 cites W1993105546 @default.
- W2104007922 cites W1993696968 @default.
- W2104007922 cites W1994025859 @default.
- W2104007922 cites W1994985645 @default.
- W2104007922 cites W1995840755 @default.
- W2104007922 cites W1997422920 @default.
- W2104007922 cites W2003884136 @default.
- W2104007922 cites W2004124985 @default.
- W2104007922 cites W2005447332 @default.
- W2104007922 cites W2007086168 @default.
- W2104007922 cites W2007135055 @default.
- W2104007922 cites W2010604180 @default.
- W2104007922 cites W2012242521 @default.
- W2104007922 cites W2012696549 @default.
- W2104007922 cites W2017588448 @default.
- W2104007922 cites W2018178609 @default.
- W2104007922 cites W2022775781 @default.
- W2104007922 cites W2023615281 @default.
- W2104007922 cites W2025180430 @default.
- W2104007922 cites W2025431637 @default.
- W2104007922 cites W2032866243 @default.
- W2104007922 cites W2039414366 @default.
- W2104007922 cites W2039579033 @default.
- W2104007922 cites W2039768088 @default.
- W2104007922 cites W2057748516 @default.
- W2104007922 cites W2057760214 @default.
- W2104007922 cites W2059600886 @default.
- W2104007922 cites W2060984632 @default.
- W2104007922 cites W2061028111 @default.
- W2104007922 cites W2066254606 @default.
- W2104007922 cites W2067057586 @default.
- W2104007922 cites W2072136747 @default.
- W2104007922 cites W2072843404 @default.
- W2104007922 cites W2073212758 @default.
- W2104007922 cites W2087414280 @default.
- W2104007922 cites W2092685243 @default.
- W2104007922 cites W2116775039 @default.
- W2104007922 cites W2118136004 @default.
- W2104007922 cites W2119025473 @default.
- W2104007922 cites W2123636362 @default.
- W2104007922 cites W2123858748 @default.
- W2104007922 cites W2124674986 @default.
- W2104007922 cites W2133062189 @default.
- W2104007922 cites W2136189697 @default.
- W2104007922 cites W2136530770 @default.
- W2104007922 cites W2139852368 @default.
- W2104007922 cites W2145944079 @default.
- W2104007922 cites W2148760296 @default.
- W2104007922 cites W2154662266 @default.
- W2104007922 cites W2155907307 @default.
- W2104007922 cites W2157223354 @default.
- W2104007922 cites W2157475667 @default.
- W2104007922 cites W2168200222 @default.
- W2104007922 cites W2171045416 @default.
- W2104007922 cites W2171074660 @default.
- W2104007922 cites W2171939070 @default.
- W2104007922 cites W2172080671 @default.
- W2104007922 cites W2230105877 @default.
- W2104007922 cites W2289063585 @default.
- W2104007922 cites W231635995 @default.
- W2104007922 cites W2914686075 @default.
- W2104007922 cites W4213024146 @default.
- W2104007922 doi "https://doi.org/10.1016/j.psychres.2014.12.029" @default.
- W2104007922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25724484" @default.
- W2104007922 hasPublicationYear "2015" @default.
- W2104007922 type Work @default.
- W2104007922 sameAs 2104007922 @default.
- W2104007922 citedByCount "15" @default.
- W2104007922 countsByYear W21040079222015 @default.