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- W2104063770 abstract "BACKGROUNDSomatic cell nuclear transfer (SCNT) requires cytoplast-mediated reprogramming of the donor nucleus. Cytoplast factors such as maturation promoting factor are implicated based on their involvement in nuclear envelope breakdown (NEBD) and premature chromosome condensation (PCC). Given prior difficulties in SCNT in primates using conventional protocols, we hypothesized that the ability of cytoplasts to induce nuclear remodeling was instrumental in efficient reprogramming." @default.
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- W2104063770 date "2007-06-11" @default.
- W2104063770 modified "2023-09-23" @default.
- W2104063770 title "Reprogramming following somatic cell nuclear transfer in primates is dependent upon nuclear remodeling" @default.
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- W2104063770 doi "https://doi.org/10.1093/humrep/dem136" @default.
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