Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104135649> ?p ?o ?g. }
- W2104135649 endingPage "349" @default.
- W2104135649 startingPage "344" @default.
- W2104135649 abstract "The association of hepatic iron overload with metabolic disorders has been coined as the insulin resistance-associated hepatic iron overload syndrome (IR-HIO).Fifty-six IR-HIO patients were phlebotomized either weekly (n = 14) or bimonthly (n = 42) and compared with C282Y homozygotes and with ten IR-HIO patients treated by a low calorie diet alone.In venesected patients, the median amount of mobilized iron was 0.6 g in 2.8 months in females and 1.8 g in 5 months in males. Mobilized iron did not differ depending on the frequency of venesections or HFE genotype. When compared with C282Y homozygotes, IR-HIO patients had a similar amount of mobilized iron, but three-fold serum ferritin levels. The presenting symptoms (chronic fatigue and/or polyarthralgias) improved in 6/7 patients. Phlebotomies were well tolerated. In patients treated by a low calorie diet, serum ferritin levels remained stable.In IR-HIO patients, body iron stores are significantly increased, overestimated by serum ferritin, not modified by a low calorie diet, and safely removed by phlebotomies. Based on these data and on studies indicating that iron excess is associated with increased risk for hepatic fibrosis, cancer and cardiovascular disorders, venesection therapy can be recommended in IR-HIO patients." @default.
- W2104135649 created "2016-06-24" @default.
- W2104135649 creator A5014869638 @default.
- W2104135649 creator A5016419093 @default.
- W2104135649 creator A5025262977 @default.
- W2104135649 creator A5037387825 @default.
- W2104135649 creator A5060977675 @default.
- W2104135649 creator A5070402826 @default.
- W2104135649 creator A5087331351 @default.
- W2104135649 creator A5089027620 @default.
- W2104135649 date "2001-09-01" @default.
- W2104135649 modified "2023-10-17" @default.
- W2104135649 title "Venesection therapy of insulin resistance-associated hepatic iron overload" @default.
- W2104135649 cites W1903511389 @default.
- W2104135649 cites W1969385146 @default.
- W2104135649 cites W1969776575 @default.
- W2104135649 cites W1984080251 @default.
- W2104135649 cites W1994166804 @default.
- W2104135649 cites W2005316756 @default.
- W2104135649 cites W2014663082 @default.
- W2104135649 cites W2026270647 @default.
- W2104135649 cites W2034684849 @default.
- W2104135649 cites W2041327900 @default.
- W2104135649 cites W2056780690 @default.
- W2104135649 cites W2058903678 @default.
- W2104135649 cites W2076826681 @default.
- W2104135649 cites W2080597450 @default.
- W2104135649 cites W2081562611 @default.
- W2104135649 cites W2093496134 @default.
- W2104135649 cites W2106991663 @default.
- W2104135649 cites W2119093527 @default.
- W2104135649 cites W2132865281 @default.
- W2104135649 cites W2143089664 @default.
- W2104135649 cites W2143543879 @default.
- W2104135649 cites W2151866938 @default.
- W2104135649 cites W2168680721 @default.
- W2104135649 cites W4252949705 @default.
- W2104135649 doi "https://doi.org/10.1016/s0168-8278(01)00147-7" @default.
- W2104135649 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11592595" @default.
- W2104135649 hasPublicationYear "2001" @default.
- W2104135649 type Work @default.
- W2104135649 sameAs 2104135649 @default.
- W2104135649 citedByCount "85" @default.
- W2104135649 countsByYear W21041356492012 @default.
- W2104135649 countsByYear W21041356492013 @default.
- W2104135649 countsByYear W21041356492014 @default.
- W2104135649 countsByYear W21041356492015 @default.
- W2104135649 countsByYear W21041356492016 @default.
- W2104135649 countsByYear W21041356492017 @default.
- W2104135649 countsByYear W21041356492019 @default.
- W2104135649 crossrefType "journal-article" @default.
- W2104135649 hasAuthorship W2104135649A5014869638 @default.
- W2104135649 hasAuthorship W2104135649A5016419093 @default.
- W2104135649 hasAuthorship W2104135649A5025262977 @default.
- W2104135649 hasAuthorship W2104135649A5037387825 @default.
- W2104135649 hasAuthorship W2104135649A5060977675 @default.
- W2104135649 hasAuthorship W2104135649A5070402826 @default.
- W2104135649 hasAuthorship W2104135649A5087331351 @default.
- W2104135649 hasAuthorship W2104135649A5089027620 @default.
- W2104135649 hasConcept C126322002 @default.
- W2104135649 hasConcept C134018914 @default.
- W2104135649 hasConcept C2776768029 @default.
- W2104135649 hasConcept C2777357209 @default.
- W2104135649 hasConcept C2777391703 @default.
- W2104135649 hasConcept C2778248108 @default.
- W2104135649 hasConcept C2778319317 @default.
- W2104135649 hasConcept C2779306644 @default.
- W2104135649 hasConcept C40438245 @default.
- W2104135649 hasConcept C71924100 @default.
- W2104135649 hasConcept C90924648 @default.
- W2104135649 hasConceptScore W2104135649C126322002 @default.
- W2104135649 hasConceptScore W2104135649C134018914 @default.
- W2104135649 hasConceptScore W2104135649C2776768029 @default.
- W2104135649 hasConceptScore W2104135649C2777357209 @default.
- W2104135649 hasConceptScore W2104135649C2777391703 @default.
- W2104135649 hasConceptScore W2104135649C2778248108 @default.
- W2104135649 hasConceptScore W2104135649C2778319317 @default.
- W2104135649 hasConceptScore W2104135649C2779306644 @default.
- W2104135649 hasConceptScore W2104135649C40438245 @default.
- W2104135649 hasConceptScore W2104135649C71924100 @default.
- W2104135649 hasConceptScore W2104135649C90924648 @default.
- W2104135649 hasIssue "3" @default.
- W2104135649 hasLocation W21041356491 @default.
- W2104135649 hasLocation W21041356492 @default.
- W2104135649 hasOpenAccess W2104135649 @default.
- W2104135649 hasPrimaryLocation W21041356491 @default.
- W2104135649 hasRelatedWork W123990863 @default.
- W2104135649 hasRelatedWork W1532551612 @default.
- W2104135649 hasRelatedWork W1892447132 @default.
- W2104135649 hasRelatedWork W1993789439 @default.
- W2104135649 hasRelatedWork W2001670904 @default.
- W2104135649 hasRelatedWork W2119692723 @default.
- W2104135649 hasRelatedWork W2159753241 @default.
- W2104135649 hasRelatedWork W2163901122 @default.
- W2104135649 hasRelatedWork W2925132551 @default.
- W2104135649 hasRelatedWork W3152300257 @default.
- W2104135649 hasVolume "35" @default.
- W2104135649 isParatext "false" @default.