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• W2104164744 abstract "Two new triterpene glycosides, coryternic acid 3-O-β-D-glucuronopyranoside (1) and coryternic acid 3-O-β-D-glucuronopyranoside-6′-O-methyl ester (2), were isolated from a MeOH extract of the tubers of Corydalis ternata. Acidic hydrolysis of 1 and 2 yielded a new triterpene as their aglycone, coryternic acid (3). The structures of these new compounds were determined through spectral analysis, including extensive 2D-NMR data. In this study we reported that triterpenoids were first isolated from the genus Corydalis. Compound 2 exhibited significant cytotoxicity against the A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines (IC50 = 15.16, 17.07, 13.32, and 11.95 µM, respectively) and significantly reduced NO production in lipopolysaccharide (LPS)-activated microglia/BV-2 cells with an IC50 value of 16.2 µM without cell toxicity." @default.
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• W2104164744 date "2011-02-21" @default.
• W2104164744 modified "2023-10-15" @default.
• W2104164744 title "New Triterpenoids from the Tubers of<i>Corydalis ternata:</i>Structural Elucidation and Bioactivity Evaluation" @default.
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• W2104164744 doi "https://doi.org/10.1055/s-0030-1270781" @default.
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