FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104184916> ?p ?o ?g. }

• W2104184916 endingPage "255" @default.
• W2104184916 startingPage "248" @default.
• W2104184916 abstract "Background We investigated the androgen receptor (AR) bioluminescense response in serum and urine before and after testosterone challenge in different genotypes of the UGT2B17 enzyme, which catalyses testosterone glucuronidation. Material and methods The androgen receptor activity was determined using a yeast-based bioluminescence assay. The androgens were analysed using LC-MS/MS, and the individuals were genotyped for UGT2B17 deletion polymorphism using real-time polymerase chain reaction. Results The serum concentrations of testosterone and dihydrotestosterone (DHT) were markedly elevated on days 2 and 4 and were still above baseline on day 15 after a dose of 500 mg testosterone enanthate. The androgenic activity in serum increased in parallel and correlated with the hormone concentrations and remained above baseline on day 15. The urinary androgenic activity increased 4–5-fold and was closely related to the unconjugated testosterone and independent of the UGT2B17 genotype. Conclusions The AR assay may serve as a complement to the urinary testosterone/epitestosterone (T/E) doping test, because this is profoundly influenced by the UGT2B17 deletion polymorphism. It may also be useful for detection of other illicit androgens in sports, or in the society, or for monitoring and diagnostics of androgen-related disorders." @default.
• W2104184916 created "2016-06-24" @default.
• W2104184916 creator A5009598036 @default.
• W2104184916 creator A5013033807 @default.
• W2104184916 creator A5033108729 @default.
• W2104184916 creator A5033420164 @default.
• W2104184916 creator A5037000255 @default.
• W2104184916 creator A5040618366 @default.
• W2104184916 creator A5041948566 @default.
• W2104184916 creator A5053216955 @default.
• W2104184916 creator A5067068922 @default.
• W2104184916 creator A5090421334 @default.
• W2104184916 date "2013-01-07" @default.
• W2104184916 modified "2023-10-14" @default.
• W2104184916 title "Testosterone challenge and androgen receptor activity in relation to UGT2B17 genotypes" @default.
• W2104184916 cites W1752182651 @default.
• W2104184916 cites W1968747826 @default.
• W2104184916 cites W1974894330 @default.
• W2104184916 cites W2002460124 @default.
• W2104184916 cites W2016671902 @default.
• W2104184916 cites W2026681536 @default.
• W2104184916 cites W2040185428 @default.
• W2104184916 cites W2046035246 @default.
• W2104184916 cites W2058850167 @default.
• W2104184916 cites W2065073682 @default.
• W2104184916 cites W2068793132 @default.
• W2104184916 cites W2075878847 @default.
• W2104184916 cites W2104218121 @default.
• W2104184916 cites W2105926570 @default.
• W2104184916 cites W2113627743 @default.
• W2104184916 cites W2129872612 @default.
• W2104184916 cites W2143121451 @default.
• W2104184916 cites W2155542054 @default.
• W2104184916 doi "https://doi.org/10.1111/eci.12037" @default.
• W2104184916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23294483" @default.
• W2104184916 hasPublicationYear "2013" @default.
• W2104184916 type Work @default.
• W2104184916 sameAs 2104184916 @default.
• W2104184916 citedByCount "18" @default.
• W2104184916 countsByYear W21041849162013 @default.
• W2104184916 countsByYear W21041849162014 @default.
• W2104184916 countsByYear W21041849162015 @default.
• W2104184916 countsByYear W21041849162016 @default.
• W2104184916 countsByYear W21041849162018 @default.
• W2104184916 countsByYear W21041849162019 @default.
• W2104184916 countsByYear W21041849162021 @default.
• W2104184916 countsByYear W21041849162022 @default.
• W2104184916 countsByYear W21041849162023 @default.
• W2104184916 crossrefType "journal-article" @default.
• W2104184916 hasAuthorship W2104184916A5009598036 @default.
• W2104184916 hasAuthorship W2104184916A5013033807 @default.
• W2104184916 hasAuthorship W2104184916A5033108729 @default.
• W2104184916 hasAuthorship W2104184916A5033420164 @default.
• W2104184916 hasAuthorship W2104184916A5037000255 @default.
• W2104184916 hasAuthorship W2104184916A5040618366 @default.
• W2104184916 hasAuthorship W2104184916A5041948566 @default.
• W2104184916 hasAuthorship W2104184916A5053216955 @default.
• W2104184916 hasAuthorship W2104184916A5067068922 @default.
• W2104184916 hasAuthorship W2104184916A5090421334 @default.
• W2104184916 hasConcept C104317684 @default.
• W2104184916 hasConcept C121608353 @default.
• W2104184916 hasConcept C126322002 @default.
• W2104184916 hasConcept C134018914 @default.
• W2104184916 hasConcept C135763542 @default.
• W2104184916 hasConcept C185592680 @default.
• W2104184916 hasConcept C2777911890 @default.
• W2104184916 hasConcept C2779279991 @default.
• W2104184916 hasConcept C2779341496 @default.
• W2104184916 hasConcept C2779881493 @default.
• W2104184916 hasConcept C2780192828 @default.
• W2104184916 hasConcept C55493867 @default.
• W2104184916 hasConcept C61367390 @default.
• W2104184916 hasConcept C71315377 @default.
• W2104184916 hasConcept C71924100 @default.
• W2104184916 hasConcept C86803240 @default.
• W2104184916 hasConceptScore W2104184916C104317684 @default.
• W2104184916 hasConceptScore W2104184916C121608353 @default.
• W2104184916 hasConceptScore W2104184916C126322002 @default.
• W2104184916 hasConceptScore W2104184916C134018914 @default.
• W2104184916 hasConceptScore W2104184916C135763542 @default.
• W2104184916 hasConceptScore W2104184916C185592680 @default.
• W2104184916 hasConceptScore W2104184916C2777911890 @default.
• W2104184916 hasConceptScore W2104184916C2779279991 @default.
• W2104184916 hasConceptScore W2104184916C2779341496 @default.
• W2104184916 hasConceptScore W2104184916C2779881493 @default.
• W2104184916 hasConceptScore W2104184916C2780192828 @default.
• W2104184916 hasConceptScore W2104184916C55493867 @default.
• W2104184916 hasConceptScore W2104184916C61367390 @default.
• W2104184916 hasConceptScore W2104184916C71315377 @default.
• W2104184916 hasConceptScore W2104184916C71924100 @default.
• W2104184916 hasConceptScore W2104184916C86803240 @default.
• W2104184916 hasIssue "3" @default.
• W2104184916 hasLocation W21041849161 @default.
• W2104184916 hasLocation W21041849162 @default.
• W2104184916 hasOpenAccess W2104184916 @default.
• W2104184916 hasPrimaryLocation W21041849161 @default.
• W2104184916 hasRelatedWork W1979102595 @default.
• W2104184916 hasRelatedWork W1979452793 @default.

• next