Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104232008> ?p ?o ?g. }
- W2104232008 endingPage "4630" @default.
- W2104232008 startingPage "4618" @default.
- W2104232008 abstract "The glycoprotein P-selectin belongs to the selectin family of cell adhesion molecules. In this study, we cloned the full-length cDNA of P-selectin from zebrafish (Danio rerio) by the method of rapid amplification of cDNA ends polymerase chain reaction (RACE-PCR). Zebrafish P-selectin cDNA is 2,800 bp and encodes a putative 868 amino acid protein with a theoretical molecular weight of 122.36 kDa and isoelectric point of 6.27. A signal peptide of 25 amino acids is predicted at the N-terminus of the putative protein. All structural domains involved in P-selectin function are conserved in the putative protein. The amino acid sequence of zebrafish P-selectin is 37% to 39% identical to that of mammalian P-selectins. Real-time quantitative PCR and whole-mount in situ hybridization analysis revealed that P-selectin was expressed in early embryonic development, the expression increased from 0.2 hpf (1-cell stage) to 72 hpf, and the expression significantly upregulated within 30 minutes of ADP induction. The results indicate that the structure of P-selectin protein is highly conserved among species and zebrafish P-selectin plays an important role in early embryonic development and probably has similar biological function to mammalian P-selectins." @default.
- W2104232008 created "2016-06-24" @default.
- W2104232008 creator A5026780331 @default.
- W2104232008 creator A5027702904 @default.
- W2104232008 creator A5062401855 @default.
- W2104232008 creator A5065172118 @default.
- W2104232008 creator A5079906436 @default.
- W2104232008 date "2010-11-17" @default.
- W2104232008 modified "2023-09-25" @default.
- W2104232008 title "Molecular Cloning and Expression Analysis of P-Selectin from Zebrafish (Danio rerio)" @default.
- W2104232008 cites W1563665002 @default.
- W2104232008 cites W1579308444 @default.
- W2104232008 cites W1688105396 @default.
- W2104232008 cites W1982176096 @default.
- W2104232008 cites W1983998987 @default.
- W2104232008 cites W1986807959 @default.
- W2104232008 cites W1988456139 @default.
- W2104232008 cites W1990941291 @default.
- W2104232008 cites W1999063996 @default.
- W2104232008 cites W2001777234 @default.
- W2104232008 cites W2004273103 @default.
- W2104232008 cites W2013438056 @default.
- W2104232008 cites W2016531738 @default.
- W2104232008 cites W2022388148 @default.
- W2104232008 cites W2038738393 @default.
- W2104232008 cites W2053188090 @default.
- W2104232008 cites W2057016253 @default.
- W2104232008 cites W2071318847 @default.
- W2104232008 cites W2072139318 @default.
- W2104232008 cites W2073408300 @default.
- W2104232008 cites W2084975606 @default.
- W2104232008 cites W2096748441 @default.
- W2104232008 cites W2104418998 @default.
- W2104232008 cites W2107277218 @default.
- W2104232008 cites W2110641306 @default.
- W2104232008 cites W2112504623 @default.
- W2104232008 cites W2128256270 @default.
- W2104232008 cites W2132908707 @default.
- W2104232008 cites W2137583122 @default.
- W2104232008 cites W2143333940 @default.
- W2104232008 cites W2160280316 @default.
- W2104232008 cites W2169304723 @default.
- W2104232008 cites W2192080449 @default.
- W2104232008 cites W2416222236 @default.
- W2104232008 cites W2418655021 @default.
- W2104232008 cites W2429485193 @default.
- W2104232008 cites W45632275 @default.
- W2104232008 doi "https://doi.org/10.3390/ijms11114618" @default.
- W2104232008 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3000104" @default.
- W2104232008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21151460" @default.
- W2104232008 hasPublicationYear "2010" @default.
- W2104232008 type Work @default.
- W2104232008 sameAs 2104232008 @default.
- W2104232008 citedByCount "5" @default.
- W2104232008 countsByYear W21042320082015 @default.
- W2104232008 countsByYear W21042320082018 @default.
- W2104232008 countsByYear W21042320082020 @default.
- W2104232008 countsByYear W21042320082021 @default.
- W2104232008 crossrefType "journal-article" @default.
- W2104232008 hasAuthorship W2104232008A5026780331 @default.
- W2104232008 hasAuthorship W2104232008A5027702904 @default.
- W2104232008 hasAuthorship W2104232008A5062401855 @default.
- W2104232008 hasAuthorship W2104232008A5065172118 @default.
- W2104232008 hasAuthorship W2104232008A5079906436 @default.
- W2104232008 hasBestOaLocation W21042320081 @default.
- W2104232008 hasConcept C104317684 @default.
- W2104232008 hasConcept C150194340 @default.
- W2104232008 hasConcept C153911025 @default.
- W2104232008 hasConcept C155619193 @default.
- W2104232008 hasConcept C16224149 @default.
- W2104232008 hasConcept C167625842 @default.
- W2104232008 hasConcept C187882448 @default.
- W2104232008 hasConcept C19924922 @default.
- W2104232008 hasConcept C2776878037 @default.
- W2104232008 hasConcept C2780384893 @default.
- W2104232008 hasConcept C50724178 @default.
- W2104232008 hasConcept C515207424 @default.
- W2104232008 hasConcept C55493867 @default.
- W2104232008 hasConcept C81439078 @default.
- W2104232008 hasConcept C86803240 @default.
- W2104232008 hasConcept C95444343 @default.
- W2104232008 hasConceptScore W2104232008C104317684 @default.
- W2104232008 hasConceptScore W2104232008C150194340 @default.
- W2104232008 hasConceptScore W2104232008C153911025 @default.
- W2104232008 hasConceptScore W2104232008C155619193 @default.
- W2104232008 hasConceptScore W2104232008C16224149 @default.
- W2104232008 hasConceptScore W2104232008C167625842 @default.
- W2104232008 hasConceptScore W2104232008C187882448 @default.
- W2104232008 hasConceptScore W2104232008C19924922 @default.
- W2104232008 hasConceptScore W2104232008C2776878037 @default.
- W2104232008 hasConceptScore W2104232008C2780384893 @default.
- W2104232008 hasConceptScore W2104232008C50724178 @default.
- W2104232008 hasConceptScore W2104232008C515207424 @default.
- W2104232008 hasConceptScore W2104232008C55493867 @default.
- W2104232008 hasConceptScore W2104232008C81439078 @default.
- W2104232008 hasConceptScore W2104232008C86803240 @default.
- W2104232008 hasConceptScore W2104232008C95444343 @default.
- W2104232008 hasIssue "11" @default.