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- W2104267515 abstract "The case histories are reported of 4 patients with extensive burns, all showing the common features of early oliguria or anuria with severe haemoglobinuria in the absence of a hypotensive phase as estimated by the systolic blood-pressure. The renal histology was studied in aspirates taken immediately after death and revealed varying phases of acute tubular necrosis. As the patients died seven hours, forty-eight hours, five days and twelve days after injury, it was possible to observe both the early and the late changes present in the tubular epithelium. The necrosis was most pronounced in the forty-eight hours' specimen corresponding clinically to total anuria. At five days tubular regeneration had commenced, coinciding clinically with the early diuretic phase. The production of these renal changes is discussed and it is suggested that renal vasospasm, haemoglobinaemia and oligaemia are the principal contributing factors. An appreciation of the renal changes is of value in the planning of treatment." @default.
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- W2104267515 date "1957-05-01" @default.
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- W2104267515 title "RENAL CHANGES IN FATAL BURNS." @default.
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- W2104267515 doi "https://doi.org/10.1111/j.1445-2197.1957.tb06388.x" @default.
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