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- W2104295909 abstract "Introduction: Patients with cerebral metastases from breast cancer have a very limited prognosis. Whole brain radiotherapy is a treatment option for these patients. cranial irradiation can cause cerebrovascular disease years after treatment, but this is unusual in adults when only a low total dose is given. Furthermore, in most patients, survival is too short to develop cerebrovascular disease. case report: A 35-year-old woman diagnosed with breast cancer, developed pulmonary and cerebral metastases after initial treatment. After whole brain radiotherapy to a dose of 20 Gy in 4-Gy-fractions, followed by chemotherapy, she was in complete remission. After 20 years, she developed a stroke. Magnetic resonance imaging scan of the brain showed an ischemic lesion consistent with small vessel disease and also diffuse white matter injury. this is an atypical location for regular vascular disease, but it may be involved after cranial irradiation. Her hypertension was adequately treated. the patient lost weight and started with acetylsalicylic acid, dipyridamole and simvastatin. Despite these preventive measures, she had two more" @default.
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- W2104295909 date "2014-01-01" @default.
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- W2104295909 title "Recurrent stroke after low dose whole brain radiotherapy for brain metastases of breast cancer" @default.
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- W2104295909 doi "https://doi.org/10.5348/ijcri-2014-01-434-cr-7" @default.
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