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- W2104324640 abstract "A series of hydroxymethyl ketones 4a–g were obtained from the corresponding halogenomethyl ketones 2a–gvia their transformation into acetoxymethyl ketones 3a–g by 18-crown-6 catalysed substitution with NaOAc followed by Novozyme 435™ catalysed ethanolysis. This convenient chemo-enzymatic route provides a mild, heavy-metal-free alternative to the direct α-hydroxylations of methyl ketones 1a–g." @default.
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- W2104324640 date "2002-01-01" @default.
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- W2104324640 title "Chemo-enzymatic preparation of hydroxymethyl ketones" @default.
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- W2104324640 doi "https://doi.org/10.1039/b206851f" @default.
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