Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104351524> ?p ?o ?g. }
- W2104351524 endingPage "1599" @default.
- W2104351524 startingPage "1583" @default.
- W2104351524 abstract "Most bacterial proteins destined to leave the cytoplasm are exported to extracellular compartments or imported into the cytoplasmic membrane via the highly conserved SecA-YEG pathway. In the present studies, the subcellular distributions of core components of this pathway, SecA and SecY, and of the secretory protein pre-AmyQ, were analysed using green fluorescent protein fusions, immunostaining and/or immunogold labelling techniques. It is shown that SecA, SecY and (pre-)AmyQ are located at specific sites near and/or in the cytoplasmic membrane of Bacillus subtilis. The localization patterns of these proteins suggest that the Sec machinery is organized in spiral-like structures along the cell, with most of the translocases organized in specific clusters along these structures. However, this localization appears to be independent of the helicoidal structures formed by the actin-like cytoskeletal proteins, MreB or Mbl. Interestingly, the specific localization of SecA is dynamic, and depends on active translation. Moreover, reducing the phosphatidylglycerol phospholipids content in the bacterial membrane results in delocalization of SecA, suggesting the involvement of membrane phospholipids in the localization process. These data show for the first time that, in contrast to the recently reported uni-ExPortal site in the coccoïd Streptococcus pyogenes, multiple sites dedicated to protein export are present in the cytoplasmic membrane of rod-shaped B. subtilis." @default.
- W2104351524 created "2016-06-24" @default.
- W2104351524 creator A5000851275 @default.
- W2104351524 creator A5002456713 @default.
- W2104351524 creator A5014567834 @default.
- W2104351524 creator A5016279411 @default.
- W2104351524 creator A5017781414 @default.
- W2104351524 creator A5019023792 @default.
- W2104351524 creator A5024844426 @default.
- W2104351524 creator A5029107560 @default.
- W2104351524 creator A5049661907 @default.
- W2104351524 creator A5069258877 @default.
- W2104351524 creator A5072821275 @default.
- W2104351524 creator A5091860197 @default.
- W2104351524 date "2004-08-03" @default.
- W2104351524 modified "2023-10-10" @default.
- W2104351524 title "Subcellular sites for bacterial protein export" @default.
- W2104351524 cites W1581713598 @default.
- W2104351524 cites W1588460021 @default.
- W2104351524 cites W1923126804 @default.
- W2104351524 cites W1968425270 @default.
- W2104351524 cites W1974721122 @default.
- W2104351524 cites W1983987888 @default.
- W2104351524 cites W1986756715 @default.
- W2104351524 cites W1993439860 @default.
- W2104351524 cites W1995304122 @default.
- W2104351524 cites W1996336244 @default.
- W2104351524 cites W1996956107 @default.
- W2104351524 cites W1998142932 @default.
- W2104351524 cites W2005160671 @default.
- W2104351524 cites W2008415333 @default.
- W2104351524 cites W2039330806 @default.
- W2104351524 cites W2039867315 @default.
- W2104351524 cites W2042720547 @default.
- W2104351524 cites W2047069686 @default.
- W2104351524 cites W2051596181 @default.
- W2104351524 cites W2053475634 @default.
- W2104351524 cites W2065259652 @default.
- W2104351524 cites W2067965488 @default.
- W2104351524 cites W2084407726 @default.
- W2104351524 cites W2092314916 @default.
- W2104351524 cites W2100837269 @default.
- W2104351524 cites W2100882223 @default.
- W2104351524 cites W2105078179 @default.
- W2104351524 cites W2105083114 @default.
- W2104351524 cites W2111086397 @default.
- W2104351524 cites W2113434530 @default.
- W2104351524 cites W2115040433 @default.
- W2104351524 cites W2132690489 @default.
- W2104351524 cites W2138081694 @default.
- W2104351524 cites W2140237288 @default.
- W2104351524 cites W2144743236 @default.
- W2104351524 cites W2155457097 @default.
- W2104351524 cites W2156489423 @default.
- W2104351524 cites W2164997719 @default.
- W2104351524 cites W2172135690 @default.
- W2104351524 cites W4256032361 @default.
- W2104351524 doi "https://doi.org/10.1111/j.1365-2958.2004.04278.x" @default.
- W2104351524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15341641" @default.
- W2104351524 hasPublicationYear "2004" @default.
- W2104351524 type Work @default.
- W2104351524 sameAs 2104351524 @default.
- W2104351524 citedByCount "138" @default.
- W2104351524 countsByYear W21043515242012 @default.
- W2104351524 countsByYear W21043515242013 @default.
- W2104351524 countsByYear W21043515242014 @default.
- W2104351524 countsByYear W21043515242015 @default.
- W2104351524 countsByYear W21043515242016 @default.
- W2104351524 countsByYear W21043515242017 @default.
- W2104351524 countsByYear W21043515242018 @default.
- W2104351524 countsByYear W21043515242019 @default.
- W2104351524 countsByYear W21043515242020 @default.
- W2104351524 countsByYear W21043515242021 @default.
- W2104351524 countsByYear W21043515242022 @default.
- W2104351524 countsByYear W21043515242023 @default.
- W2104351524 crossrefType "journal-article" @default.
- W2104351524 hasAuthorship W2104351524A5000851275 @default.
- W2104351524 hasAuthorship W2104351524A5002456713 @default.
- W2104351524 hasAuthorship W2104351524A5014567834 @default.
- W2104351524 hasAuthorship W2104351524A5016279411 @default.
- W2104351524 hasAuthorship W2104351524A5017781414 @default.
- W2104351524 hasAuthorship W2104351524A5019023792 @default.
- W2104351524 hasAuthorship W2104351524A5024844426 @default.
- W2104351524 hasAuthorship W2104351524A5029107560 @default.
- W2104351524 hasAuthorship W2104351524A5049661907 @default.
- W2104351524 hasAuthorship W2104351524A5069258877 @default.
- W2104351524 hasAuthorship W2104351524A5072821275 @default.
- W2104351524 hasAuthorship W2104351524A5091860197 @default.
- W2104351524 hasBestOaLocation W21043515242 @default.
- W2104351524 hasConcept C104317684 @default.
- W2104351524 hasConcept C105702510 @default.
- W2104351524 hasConcept C140051345 @default.
- W2104351524 hasConcept C142669718 @default.
- W2104351524 hasConcept C144647389 @default.
- W2104351524 hasConcept C1491633281 @default.
- W2104351524 hasConcept C190062978 @default.
- W2104351524 hasConcept C2776879804 @default.
- W2104351524 hasConcept C2777272437 @default.