Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104391100> ?p ?o ?g. }
- W2104391100 endingPage "233" @default.
- W2104391100 startingPage "225" @default.
- W2104391100 abstract "Interleukin 8 (IL8) is usually produced in both epithelial and monocytic cells during bacterial infections, causing inflammation. Helicobacter pylori induces production of IL8 from gastric epithelial cells via its cag pathogenicity island (cag PAI) system, LPS and outer-membrane protein. In some bacteria, heat-shock protein 60 (HSP60) also elicits a strong pro-inflammatory response in cells of the innate immune system. Three recombinant H. pylori HSP60 (rHSP60) proteins of different sizes were produced and one of these was used to raise two monoclonal antibodies (2E7 and 7B5). IL8 production was found to be induced in cultured monocytic cells treated with H. pylori cells or rHSP60 proteins, as measured by ELISA, and the amount of IL8 produced was dose-dependent. Pre-incubation of H. pylori cells or rHSP60 preparations with the antibody 2E7 significantly inhibited IL8 production from monocytic cells. These results indicated that HSP60 is closely associated with IL8 production in monocytic cells." @default.
- W2104391100 created "2016-06-24" @default.
- W2104391100 creator A5000258453 @default.
- W2104391100 creator A5001121988 @default.
- W2104391100 creator A5003210360 @default.
- W2104391100 creator A5018383898 @default.
- W2104391100 creator A5029095534 @default.
- W2104391100 creator A5048182032 @default.
- W2104391100 creator A5057537700 @default.
- W2104391100 creator A5069051997 @default.
- W2104391100 creator A5069864602 @default.
- W2104391100 creator A5072111526 @default.
- W2104391100 creator A5081234240 @default.
- W2104391100 creator A5088465415 @default.
- W2104391100 date "2005-03-01" @default.
- W2104391100 modified "2023-09-26" @default.
- W2104391100 title "Helicobacter pylori heat-shock protein 60 induces production of the pro-inflammatory cytokine IL8 in monocytic cells" @default.
- W2104391100 cites W1498007334 @default.
- W2104391100 cites W1534378060 @default.
- W2104391100 cites W1553853809 @default.
- W2104391100 cites W1909410665 @default.
- W2104391100 cites W1925847394 @default.
- W2104391100 cites W1957957211 @default.
- W2104391100 cites W1972345745 @default.
- W2104391100 cites W2016103677 @default.
- W2104391100 cites W2022076163 @default.
- W2104391100 cites W2046595571 @default.
- W2104391100 cites W2047053776 @default.
- W2104391100 cites W2060119050 @default.
- W2104391100 cites W2061173446 @default.
- W2104391100 cites W2066739766 @default.
- W2104391100 cites W2067505859 @default.
- W2104391100 cites W2069711320 @default.
- W2104391100 cites W2073204639 @default.
- W2104391100 cites W2075642347 @default.
- W2104391100 cites W2095736339 @default.
- W2104391100 cites W2101571688 @default.
- W2104391100 cites W2104357791 @default.
- W2104391100 cites W2110625090 @default.
- W2104391100 cites W2116898839 @default.
- W2104391100 cites W2123904147 @default.
- W2104391100 cites W2124635565 @default.
- W2104391100 cites W2127047553 @default.
- W2104391100 cites W2129372473 @default.
- W2104391100 cites W2131153807 @default.
- W2104391100 cites W2134003268 @default.
- W2104391100 cites W2134223533 @default.
- W2104391100 cites W2136143589 @default.
- W2104391100 cites W2137178382 @default.
- W2104391100 cites W2137787156 @default.
- W2104391100 cites W2143111837 @default.
- W2104391100 cites W2146737004 @default.
- W2104391100 cites W2149153060 @default.
- W2104391100 cites W2320937221 @default.
- W2104391100 doi "https://doi.org/10.1099/jmm.0.45871-0" @default.
- W2104391100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15713605" @default.
- W2104391100 hasPublicationYear "2005" @default.
- W2104391100 type Work @default.
- W2104391100 sameAs 2104391100 @default.
- W2104391100 citedByCount "23" @default.
- W2104391100 countsByYear W21043911002013 @default.
- W2104391100 countsByYear W21043911002016 @default.
- W2104391100 countsByYear W21043911002018 @default.
- W2104391100 countsByYear W21043911002020 @default.
- W2104391100 countsByYear W21043911002022 @default.
- W2104391100 crossrefType "journal-article" @default.
- W2104391100 hasAuthorship W2104391100A5000258453 @default.
- W2104391100 hasAuthorship W2104391100A5001121988 @default.
- W2104391100 hasAuthorship W2104391100A5003210360 @default.
- W2104391100 hasAuthorship W2104391100A5018383898 @default.
- W2104391100 hasAuthorship W2104391100A5029095534 @default.
- W2104391100 hasAuthorship W2104391100A5048182032 @default.
- W2104391100 hasAuthorship W2104391100A5057537700 @default.
- W2104391100 hasAuthorship W2104391100A5069051997 @default.
- W2104391100 hasAuthorship W2104391100A5069864602 @default.
- W2104391100 hasAuthorship W2104391100A5072111526 @default.
- W2104391100 hasAuthorship W2104391100A5081234240 @default.
- W2104391100 hasAuthorship W2104391100A5088465415 @default.
- W2104391100 hasBestOaLocation W21043911001 @default.
- W2104391100 hasConcept C104317684 @default.
- W2104391100 hasConcept C13373296 @default.
- W2104391100 hasConcept C136449434 @default.
- W2104391100 hasConcept C203014093 @default.
- W2104391100 hasConcept C205260736 @default.
- W2104391100 hasConcept C2776409635 @default.
- W2104391100 hasConcept C2776914184 @default.
- W2104391100 hasConcept C2778690821 @default.
- W2104391100 hasConcept C2781184567 @default.
- W2104391100 hasConcept C50345908 @default.
- W2104391100 hasConcept C54355233 @default.
- W2104391100 hasConcept C55493867 @default.
- W2104391100 hasConcept C68324877 @default.
- W2104391100 hasConcept C74172505 @default.
- W2104391100 hasConcept C86803240 @default.
- W2104391100 hasConcept C8891405 @default.
- W2104391100 hasConcept C89423630 @default.
- W2104391100 hasConceptScore W2104391100C104317684 @default.
- W2104391100 hasConceptScore W2104391100C13373296 @default.