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• W2104414253 abstract "ABSTRACT The coronavirus nucleocapsid (N) protein is a virion structural protein. It also functions, however, in an unknown way in viral replication and localizes to the viral replication-transcription complexes (RTCs). Here we investigated, using recombinant murine coronaviruses expressing green fluorescent protein (GFP)-tagged versions of the N protein, the dynamics of its interactions with the RTCs and the domain(s) involved. Using fluorescent recovery after photobleaching, we showed that the N protein, unlike the nonstructural protein 2, is dynamically associated with the RTCs. Recruitment of the N protein to the RTCs requires the C-terminal N2b domain, which interacts with other N proteins in an RNA-independent manner." @default.
• W2104414253 created "2016-06-24" @default.
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• W2104414253 date "2010-11-01" @default.
• W2104414253 modified "2023-10-14" @default.
• W2104414253 title "The Coronavirus Nucleocapsid Protein Is Dynamically Associated with the Replication-Transcription Complexes" @default.
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• W2104414253 doi "https://doi.org/10.1128/jvi.00569-10" @default.
• W2104414253 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2953146" @default.
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