Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104470625> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2104470625 abstract "Intramolecular compact structures formed by high molecular weight circular superhelical DNA molecules due to interaction with synthetic oligopeptide trivaline (1) were studied by atomic force and electron microscopy. Three DNA preparations were used: plasmids pTbol, pRX10 and cosmid 27,877, with sizes 6,120 bp, 10,500 bp and 44,890 bp respectively. Plasmid pTbo1 and pRX10 preparations along with monomers contained significant amount of dimers and trimers. Main structures in all preparations observed were compact particles, which coincide in their appearance and compaction coefficient (3,5-3,7) with triple rings described earlier. The size and structure characteristics of triple rings and other compact particles on atomic force images in general coincide with those obtained by EM (2). AFM (3) images allow to get additional information about the ultrastructural organization and arrangement of DNA fibers within the compact structures. Along with triple rings in pTbol and pRX10-TVP complexes significant amount of compact structures were observed having the shape of two or three compact rings attached to each other by a region of compact fibre. Basing on the data of contour length measurements and the shape of the particles it was concluded that these structures were formed due to compaction of dimeric and trimeric circular DNA molecules. Structures consisting of several attached to each other triple rings were not found for pTbol, pRX10 monomers or cosmid preparations--TVP complexes where only single triple rings were observed. The conclusion is made that initiation of compact fibre formation within the circular molecules depends on the primary structure and for dimeric or trimeric circular molecules two or three compaction initiation points are present, located in each monomer unit within one circular DNA molecule. The nucleotide sequence dependent compaction mechanism providing independent compaction of portions of one circular molecule can be of interest for understanding of DNA compaction processes in vivo." @default.
- W2104470625 created "2016-06-24" @default.
- W2104470625 creator A5000026575 @default.
- W2104470625 creator A5004387448 @default.
- W2104470625 creator A5011889177 @default.
- W2104470625 creator A5023446145 @default.
- W2104470625 creator A5035017699 @default.
- W2104470625 creator A5042826449 @default.
- W2104470625 creator A5046712786 @default.
- W2104470625 creator A5052374235 @default.
- W2104470625 date "2000-02-01" @default.
- W2104470625 modified "2023-09-26" @default.
- W2104470625 title "Atomic Force and Electron Microscopy of High Molecular Weight Circular DNA Complexes with Synthetic Oligopeptide Trivaline" @default.
- W2104470625 cites W1963942961 @default.
- W2104470625 cites W1990000938 @default.
- W2104470625 cites W2008125587 @default.
- W2104470625 cites W2020975457 @default.
- W2104470625 cites W2080324294 @default.
- W2104470625 cites W2083621518 @default.
- W2104470625 cites W2085538058 @default.
- W2104470625 cites W2107511168 @default.
- W2104470625 cites W2180298057 @default.
- W2104470625 cites W2214716537 @default.
- W2104470625 doi "https://doi.org/10.1080/07391102.2000.10506559" @default.
- W2104470625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10698106" @default.
- W2104470625 hasPublicationYear "2000" @default.
- W2104470625 type Work @default.
- W2104470625 sameAs 2104470625 @default.
- W2104470625 citedByCount "4" @default.
- W2104470625 crossrefType "journal-article" @default.
- W2104470625 hasAuthorship W2104470625A5000026575 @default.
- W2104470625 hasAuthorship W2104470625A5004387448 @default.
- W2104470625 hasAuthorship W2104470625A5011889177 @default.
- W2104470625 hasAuthorship W2104470625A5023446145 @default.
- W2104470625 hasAuthorship W2104470625A5035017699 @default.
- W2104470625 hasAuthorship W2104470625A5042826449 @default.
- W2104470625 hasAuthorship W2104470625A5046712786 @default.
- W2104470625 hasAuthorship W2104470625A5052374235 @default.
- W2104470625 hasConcept C120665830 @default.
- W2104470625 hasConcept C121332964 @default.
- W2104470625 hasConcept C166940927 @default.
- W2104470625 hasConcept C178790620 @default.
- W2104470625 hasConcept C185592680 @default.
- W2104470625 hasConcept C192562407 @default.
- W2104470625 hasConcept C32909587 @default.
- W2104470625 hasConcept C521977710 @default.
- W2104470625 hasConcept C552990157 @default.
- W2104470625 hasConcept C55493867 @default.
- W2104470625 hasConcept C8010536 @default.
- W2104470625 hasConcept C93877712 @default.
- W2104470625 hasConceptScore W2104470625C120665830 @default.
- W2104470625 hasConceptScore W2104470625C121332964 @default.
- W2104470625 hasConceptScore W2104470625C166940927 @default.
- W2104470625 hasConceptScore W2104470625C178790620 @default.
- W2104470625 hasConceptScore W2104470625C185592680 @default.
- W2104470625 hasConceptScore W2104470625C192562407 @default.
- W2104470625 hasConceptScore W2104470625C32909587 @default.
- W2104470625 hasConceptScore W2104470625C521977710 @default.
- W2104470625 hasConceptScore W2104470625C552990157 @default.
- W2104470625 hasConceptScore W2104470625C55493867 @default.
- W2104470625 hasConceptScore W2104470625C8010536 @default.
- W2104470625 hasConceptScore W2104470625C93877712 @default.
- W2104470625 hasLocation W21044706251 @default.
- W2104470625 hasLocation W21044706252 @default.
- W2104470625 hasOpenAccess W2104470625 @default.
- W2104470625 hasPrimaryLocation W21044706251 @default.
- W2104470625 hasRelatedWork W1974962194 @default.
- W2104470625 hasRelatedWork W1982657684 @default.
- W2104470625 hasRelatedWork W1988204998 @default.
- W2104470625 hasRelatedWork W1995522249 @default.
- W2104470625 hasRelatedWork W1997008641 @default.
- W2104470625 hasRelatedWork W2008911030 @default.
- W2104470625 hasRelatedWork W2039721087 @default.
- W2104470625 hasRelatedWork W2043593701 @default.
- W2104470625 hasRelatedWork W2043897310 @default.
- W2104470625 hasRelatedWork W2060310459 @default.
- W2104470625 hasRelatedWork W2085364886 @default.
- W2104470625 hasRelatedWork W2087250059 @default.
- W2104470625 hasRelatedWork W2094436267 @default.
- W2104470625 hasRelatedWork W2113781823 @default.
- W2104470625 hasRelatedWork W2121264132 @default.
- W2104470625 hasRelatedWork W2163274470 @default.
- W2104470625 hasRelatedWork W2223764435 @default.
- W2104470625 hasRelatedWork W2341783703 @default.
- W2104470625 hasRelatedWork W2407022152 @default.
- W2104470625 hasRelatedWork W2418287398 @default.
- W2104470625 isParatext "false" @default.
- W2104470625 isRetracted "false" @default.
- W2104470625 magId "2104470625" @default.
- W2104470625 workType "article" @default.