Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104483500> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2104483500 endingPage "1813" @default.
- W2104483500 startingPage "1809" @default.
- W2104483500 abstract "The HSV-2 tumour system was originally derived from an in vitro transformation of HEF by inactivated HSV-2. When injected s.c. these cells produce spindle-cell sarcomas which are metastatic at a low level. Detailed cytogenetic studies have provided evidence of tumour x normal host cell fusion in two of seven cell lines derived from metastatic lung deposits (Met D and Met G). This is the first report, in an unselected, intraspecific system, of in vivo cell fusion in spontaneous metastasis. The cells of Met D consisted of a heterogeneous population of fused and unfused tumour cells, whereas those of Met G were a homogeneous population of hybrid cells. Fusion, therefore, is likely to have occurred after metastasis in Met D and prior to, or at, metastasis in Met G. The fused cells of Met D showed comparatively little chromosome loss, while in Met G there was loss of approaching one haploid set of chromosomes. The generation of metastatic variants by cell fusion contributes to genetic diversity and emphasizes the importance of tumour heterogeneity in malignancy." @default.
- W2104483500 created "2016-06-24" @default.
- W2104483500 creator A5013296674 @default.
- W2104483500 creator A5014842076 @default.
- W2104483500 creator A5035759500 @default.
- W2104483500 date "1989-12-01" @default.
- W2104483500 modified "2023-09-23" @default.
- W2104483500 title "In vivo tumour × host cell fusion in spontaneous syrian hamster metastasis" @default.
- W2104483500 cites W1525850954 @default.
- W2104483500 cites W1534962750 @default.
- W2104483500 cites W1547590807 @default.
- W2104483500 cites W1799234753 @default.
- W2104483500 cites W1877171832 @default.
- W2104483500 cites W1970280675 @default.
- W2104483500 cites W1970440374 @default.
- W2104483500 cites W1977086729 @default.
- W2104483500 cites W2003591846 @default.
- W2104483500 cites W2029185993 @default.
- W2104483500 cites W2038781366 @default.
- W2104483500 cites W2055699486 @default.
- W2104483500 cites W2073598161 @default.
- W2104483500 cites W2077518088 @default.
- W2104483500 cites W2078296835 @default.
- W2104483500 cites W2139322764 @default.
- W2104483500 cites W2417927222 @default.
- W2104483500 doi "https://doi.org/10.1016/0277-5379(89)90352-0" @default.
- W2104483500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2632263" @default.
- W2104483500 hasPublicationYear "1989" @default.
- W2104483500 type Work @default.
- W2104483500 sameAs 2104483500 @default.
- W2104483500 citedByCount "4" @default.
- W2104483500 crossrefType "journal-article" @default.
- W2104483500 hasAuthorship W2104483500A5013296674 @default.
- W2104483500 hasAuthorship W2104483500A5014842076 @default.
- W2104483500 hasAuthorship W2104483500A5035759500 @default.
- W2104483500 hasConcept C121608353 @default.
- W2104483500 hasConcept C142724271 @default.
- W2104483500 hasConcept C1491633281 @default.
- W2104483500 hasConcept C153911025 @default.
- W2104483500 hasConcept C207001950 @default.
- W2104483500 hasConcept C2778575167 @default.
- W2104483500 hasConcept C2779013556 @default.
- W2104483500 hasConcept C2779399171 @default.
- W2104483500 hasConcept C2908647359 @default.
- W2104483500 hasConcept C502942594 @default.
- W2104483500 hasConcept C54355233 @default.
- W2104483500 hasConcept C71924100 @default.
- W2104483500 hasConcept C81885089 @default.
- W2104483500 hasConcept C86803240 @default.
- W2104483500 hasConcept C92488253 @default.
- W2104483500 hasConcept C99454951 @default.
- W2104483500 hasConceptScore W2104483500C121608353 @default.
- W2104483500 hasConceptScore W2104483500C142724271 @default.
- W2104483500 hasConceptScore W2104483500C1491633281 @default.
- W2104483500 hasConceptScore W2104483500C153911025 @default.
- W2104483500 hasConceptScore W2104483500C207001950 @default.
- W2104483500 hasConceptScore W2104483500C2778575167 @default.
- W2104483500 hasConceptScore W2104483500C2779013556 @default.
- W2104483500 hasConceptScore W2104483500C2779399171 @default.
- W2104483500 hasConceptScore W2104483500C2908647359 @default.
- W2104483500 hasConceptScore W2104483500C502942594 @default.
- W2104483500 hasConceptScore W2104483500C54355233 @default.
- W2104483500 hasConceptScore W2104483500C71924100 @default.
- W2104483500 hasConceptScore W2104483500C81885089 @default.
- W2104483500 hasConceptScore W2104483500C86803240 @default.
- W2104483500 hasConceptScore W2104483500C92488253 @default.
- W2104483500 hasConceptScore W2104483500C99454951 @default.
- W2104483500 hasIssue "12" @default.
- W2104483500 hasLocation W21044835001 @default.
- W2104483500 hasLocation W21044835002 @default.
- W2104483500 hasOpenAccess W2104483500 @default.
- W2104483500 hasPrimaryLocation W21044835001 @default.
- W2104483500 hasRelatedWork W1606256000 @default.
- W2104483500 hasRelatedWork W1966037124 @default.
- W2104483500 hasRelatedWork W2005691864 @default.
- W2104483500 hasRelatedWork W2021043674 @default.
- W2104483500 hasRelatedWork W2037321113 @default.
- W2104483500 hasRelatedWork W2103969293 @default.
- W2104483500 hasRelatedWork W2138953772 @default.
- W2104483500 hasRelatedWork W2142277157 @default.
- W2104483500 hasRelatedWork W2362184876 @default.
- W2104483500 hasRelatedWork W2473716119 @default.
- W2104483500 hasVolume "25" @default.
- W2104483500 isParatext "false" @default.
- W2104483500 isRetracted "false" @default.
- W2104483500 magId "2104483500" @default.
- W2104483500 workType "article" @default.