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• W2104484273 endingPage "258" @default.
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• W2104484273 abstract "Dicopper(II) complexes of a series of different pyrazolate-based dinucleating ligands [L1](-)-[L4](-) have been synthesized and characterized structurally and spectroscopically. A major difference between the four complexes is the individual metal-metal separation that is enforced by the chelating side arms of the pyrazolate ligand scaffold: it varies from 3.45 A in 2 x (BF4)4 to 4.53 A in 4 x (ClO4)2. All complexes have been evaluated as model systems for the catechol oxidase enzyme by using 3,5-di-tert-butylcatechole (DTBC) as the test substrate. They were shown to exhibit very different catecholase activities ranging from very efficient to poor catalysts (k(obs) between 2430+/-202 and 22.8+/-1.2 h(-1)), with an order of decreasing activity 2 x (ClO4)4 > 1 x (ClO4)2 > 3 x (ClO4)2 >> 4 x (ClO4)2. A correlation of the catecholase activities with the variation in Cu...Cu distances, as well as other effects resulting from the distinct redox potentials, neighboring groups, and the individual coordination spheres are discussed. Saturation behavior for the rate dependence on substrate concentration was observed in only two cases, that is, for the most active 2 x (ClO4)4 and for the least active 4 x (ClO4)2, whereas a catalytic rate that is almost independent of substrate concentration (within the range studied) was observed for 1 x (ClO4)2 and 3 x (ClO4)2. H2O2 was detected as the product of O2 reduction in the catecholase reaction of the three most active systems. The structures of the adducts of L3Cu2 and L4Cu2 with a substrate analogue (tetrachlorocatecholate, TCC) suggest a bidentate substrate coordination to only one of the copper ions for those catalysts that feature short ligand side arms and correspondingly exhibit larger metal-metal separations; this possibly contributes to the lower activity of these systems. TCC binding is supported by several H-bonding interactions to water molecules at the adjacent copper or to ligand-side-arm N-donors; this emphasizes the importance of functional groups in proximity to the bimetallic active site." @default.
• W2104484273 created "2016-06-24" @default.
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• W2104484273 date "2002-01-04" @default.
• W2104484273 modified "2023-10-14" @default.
• W2104484273 title "Tuning the Activity of Catechol Oxidase Model Complexes by Geometric Changes of the Dicopper Core" @default.
• W2104484273 cites W1535193939 @default.
• W2104484273 cites W1558340799 @default.
• W2104484273 cites W1898591991 @default.
• W2104484273 cites W1966114000 @default.
• W2104484273 cites W1970242511 @default.
• W2104484273 cites W1971515732 @default.
• W2104484273 cites W1975817905 @default.
• W2104484273 cites W1977334206 @default.
• W2104484273 cites W1977925490 @default.
• W2104484273 cites W1981704948 @default.
• W2104484273 cites W1981761820 @default.
• W2104484273 cites W1981902642 @default.
• W2104484273 cites W1984455831 @default.
• W2104484273 cites W1984480297 @default.
• W2104484273 cites W1986038979 @default.
• W2104484273 cites W1987063649 @default.
• W2104484273 cites W1991677766 @default.
• W2104484273 cites W1992165091 @default.
• W2104484273 cites W1993727472 @default.
• W2104484273 cites W1994103683 @default.
• W2104484273 cites W1996096107 @default.
• W2104484273 cites W1998147495 @default.
• W2104484273 cites W1998179744 @default.
• W2104484273 cites W2000375726 @default.
• W2104484273 cites W2005234903 @default.
• W2104484273 cites W2005622619 @default.
• W2104484273 cites W2008013116 @default.
• W2104484273 cites W2010010399 @default.
• W2104484273 cites W2011918357 @default.
• W2104484273 cites W2015805148 @default.
• W2104484273 cites W2016193130 @default.
• W2104484273 cites W2019347060 @default.
• W2104484273 cites W2022276904 @default.
• W2104484273 cites W2023809317 @default.
• W2104484273 cites W2025362358 @default.
• W2104484273 cites W2025637852 @default.
• W2104484273 cites W2026427334 @default.
• W2104484273 cites W2028291957 @default.
• W2104484273 cites W2036285296 @default.
• W2104484273 cites W2036591933 @default.
• W2104484273 cites W2047380423 @default.
• W2104484273 cites W2047940948 @default.
• W2104484273 cites W2049597257 @default.
• W2104484273 cites W2058259904 @default.
• W2104484273 cites W2059652206 @default.
• W2104484273 cites W2061356043 @default.
• W2104484273 cites W2071894609 @default.
• W2104484273 cites W2073148907 @default.
• W2104484273 cites W2075208279 @default.
• W2104484273 cites W2078571931 @default.
• W2104484273 cites W2079948241 @default.
• W2104484273 cites W2081851307 @default.
• W2104484273 cites W2085525201 @default.
• W2104484273 cites W2086839097 @default.
• W2104484273 cites W2088034681 @default.
• W2104484273 cites W2090633924 @default.
• W2104484273 cites W2091960606 @default.
• W2104484273 cites W2093808572 @default.
• W2104484273 cites W2102455520 @default.
• W2104484273 cites W2105249240 @default.
• W2104484273 cites W2146533861 @default.
• W2104484273 cites W2154264198 @default.
• W2104484273 cites W2163339819 @default.
• W2104484273 cites W2164077352 @default.
• W2104484273 cites W2165385828 @default.
• W2104484273 cites W2169912371 @default.
• W2104484273 cites W2227573572 @default.
• W2104484273 cites W2950812332 @default.
• W2104484273 cites W2953090859 @default.
• W2104484273 cites W3004480158 @default.
• W2104484273 cites W3004939862 @default.
• W2104484273 cites W4238998380 @default.
• W2104484273 doi "https://doi.org/10.1002/1521-3765(20020104)8:1<247::aid-chem247>3.0.co;2-p" @default.
• W2104484273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11822456" @default.
• W2104484273 hasPublicationYear "2002" @default.
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