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• W2104492546 abstract "The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often modify this structure. An important open question concerns the role of brain modularity in sustaining the critical behaviour of spontaneous activity. Here we analyse the neuronal activity of a model, successful in reproducing on non-modular networks the scaling behaviour observed in experimental data, on a modular network implementing the main statistical features measured in human brain. We show that on a modular network, regardless the strength of the synaptic connections or the modular size and number, activity is never fully scale-free. Neuronal avalanches can invade different modules which results in an activity depression, hindering further avalanche propagation. Critical behaviour is solely recovered if inter-module connections are added, modifying the modular into a more random structure." @default.
• W2104492546 created "2016-06-24" @default.
• W2104492546 creator A5062795587 @default.
• W2104492546 creator A5065071611 @default.
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• W2104492546 date "2014-03-13" @default.
• W2104492546 modified "2023-10-03" @default.
• W2104492546 title "Brain modularity controls the critical behavior of spontaneous activity" @default.
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• W2104492546 doi "https://doi.org/10.1038/srep04312" @default.
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