FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104514705> ?p ?o ?g. }

• W2104514705 abstract "Abstract Background After ovulation in the cow, the corpus luteum (CL) rapidly develops within a few days with angiogenesis and progesterone production. CL formation resembles an inflammatory response due to the influx of immune cells. Neutrophils play a role in host defense and inflammation, and secrete chemoattractants to stimulate angiogenesis. We therefore hypothesized that neutrophils infiltrate in the developing CL from just after ovulation and may play a role in angiogenesis of the CL. Methods and Results Polymorphonuclear neutrophils (PMN) were detected in CL tissue by Pas-staining, and interleukin-8 (IL-8, a neutrophil-specific chemoattractant) was measured in supernatant of the CL tissue culture: considerable amounts of PMNs and the high level of IL-8 were observed during the early luteal phase (days 1-4 of the estrous cycle). PMNs and IL-8 were low levels in the mid and late luteal phases, but IL-8 was increased during luteal regression. The PMN migration in vitro was stimulated by the supernatant from the early CL but not from the mid CL, and this activity was inhibited by neutralizing with an anti-IL-8 antibody, indicating the major role of IL-8 in inducing active PMN migration in the early CL. Moreover, IL-8 stimulated proliferation of CL-derived endothelial cells (LECs), and both the supernatant of activated PMNs and IL-8 stimulated formation of capillary-like structures of LECs. Conclusion PMNs migrate into the early CL partially due to its major chemoattractant IL-8 produced at high levels in the CL, and PMNs is a potential regulator of angiogenesis together with IL-8 in developing CL in the cow." @default.
• W2104514705 created "2016-06-24" @default.
• W2104514705 creator A5016429154 @default.
• W2104514705 creator A5020012457 @default.
• W2104514705 creator A5050021829 @default.
• W2104514705 creator A5054994098 @default.
• W2104514705 creator A5059138509 @default.
• W2104514705 creator A5061027903 @default.
• W2104514705 creator A5083145735 @default.
• W2104514705 date "2011-06-08" @default.
• W2104514705 modified "2023-10-18" @default.
• W2104514705 title "Evidence that polymorphonuclear neutrophils infiltrate into the developing corpus luteum and promote angiogenesis with interleukin-8 in the cow" @default.
• W2104514705 cites W1575791963 @default.
• W2104514705 cites W1973277351 @default.
• W2104514705 cites W1975694155 @default.
• W2104514705 cites W1986851731 @default.
• W2104514705 cites W1989596343 @default.
• W2104514705 cites W2000706956 @default.
• W2104514705 cites W2005713441 @default.
• W2104514705 cites W2006385139 @default.
• W2104514705 cites W2012269283 @default.
• W2104514705 cites W2022021401 @default.
• W2104514705 cites W2029572364 @default.
• W2104514705 cites W2029790299 @default.
• W2104514705 cites W2032704369 @default.
• W2104514705 cites W2041289994 @default.
• W2104514705 cites W2048278405 @default.
• W2104514705 cites W2054490284 @default.
• W2104514705 cites W2055575728 @default.
• W2104514705 cites W2066769255 @default.
• W2104514705 cites W2067475619 @default.
• W2104514705 cites W2072790320 @default.
• W2104514705 cites W2074231203 @default.
• W2104514705 cites W2077491140 @default.
• W2104514705 cites W2085119204 @default.
• W2104514705 cites W2088161473 @default.
• W2104514705 cites W2088343796 @default.
• W2104514705 cites W2093096968 @default.
• W2104514705 cites W2093899119 @default.
• W2104514705 cites W2098793470 @default.
• W2104514705 cites W2100462908 @default.
• W2104514705 cites W2101246537 @default.
• W2104514705 cites W2107994102 @default.
• W2104514705 cites W2109840334 @default.
• W2104514705 cites W2111279091 @default.
• W2104514705 cites W2111544730 @default.
• W2104514705 cites W2129087118 @default.
• W2104514705 cites W2141265451 @default.
• W2104514705 cites W2147005315 @default.
• W2104514705 cites W2149053581 @default.
• W2104514705 cites W2159360711 @default.
• W2104514705 cites W2338288098 @default.
• W2104514705 cites W2397387704 @default.
• W2104514705 cites W4243025917 @default.
• W2104514705 cites W4294216491 @default.
• W2104514705 cites W51563066 @default.
• W2104514705 doi "https://doi.org/10.1186/1477-7827-9-79" @default.
• W2104514705 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3129584" @default.
• W2104514705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21651784" @default.
• W2104514705 hasPublicationYear "2011" @default.
• W2104514705 type Work @default.
• W2104514705 sameAs 2104514705 @default.
• W2104514705 citedByCount "67" @default.
• W2104514705 countsByYear W21045147052012 @default.
• W2104514705 countsByYear W21045147052013 @default.
• W2104514705 countsByYear W21045147052014 @default.
• W2104514705 countsByYear W21045147052015 @default.
• W2104514705 countsByYear W21045147052016 @default.
• W2104514705 countsByYear W21045147052017 @default.
• W2104514705 countsByYear W21045147052018 @default.
• W2104514705 countsByYear W21045147052019 @default.
• W2104514705 countsByYear W21045147052020 @default.
• W2104514705 countsByYear W21045147052021 @default.
• W2104514705 countsByYear W21045147052022 @default.
• W2104514705 countsByYear W21045147052023 @default.
• W2104514705 crossrefType "journal-article" @default.
• W2104514705 hasAuthorship W2104514705A5016429154 @default.
• W2104514705 hasAuthorship W2104514705A5020012457 @default.
• W2104514705 hasAuthorship W2104514705A5050021829 @default.
• W2104514705 hasAuthorship W2104514705A5054994098 @default.
• W2104514705 hasAuthorship W2104514705A5059138509 @default.
• W2104514705 hasAuthorship W2104514705A5061027903 @default.
• W2104514705 hasAuthorship W2104514705A5083145735 @default.
• W2104514705 hasBestOaLocation W21045147051 @default.
• W2104514705 hasConcept C126322002 @default.
• W2104514705 hasConcept C134018914 @default.
• W2104514705 hasConcept C143228043 @default.
• W2104514705 hasConcept C16685009 @default.
• W2104514705 hasConcept C170493617 @default.
• W2104514705 hasConcept C185592680 @default.
• W2104514705 hasConcept C187785154 @default.
• W2104514705 hasConcept C203014093 @default.
• W2104514705 hasConcept C2776608385 @default.
• W2104514705 hasConcept C2776914184 @default.
• W2104514705 hasConcept C2777702977 @default.
• W2104514705 hasConcept C2778324911 @default.
• W2104514705 hasConcept C2780394083 @default.
• W2104514705 hasConcept C54166955 @default.
• W2104514705 hasConcept C68324877 @default.
• W2104514705 hasConcept C71315377 @default.

• next