FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104602109> ?p ?o ?g. }

• W2104602109 abstract "In May 2010, J. Craig Venter and his team announced the creation of a “synthetic cell,” or as the team described it, a process of “synthesis, assembly, cloning, and successful transplantation [of a synthetic genome] to create a new cell controlled by this synthetic genome.” They chose to start with a simple bacterium, Mycoplasma genitalium (“M. genitalium”) because it has “the smallest complement of genes of any known organism capable of independent growth in the laboratory.” Using chemical enzymes and live bacteria, they were able to replicate the genome sequence of M. genitalium and then transplant it into a natural cell controlled by the synthetic genome. Although the team had not created a new cell entirely from chemicals, their research demonstrates progress towards that end.The creation of a synthetic genome is an important advancement in synthetic biology, “an emerging field of research that combines elements of biology, engineering, genetics, chemistry, and computer science.” Synthetic biology research often begins with a “[t]op-down” approach, using existing genes and other materials as parts to be analyzed or possibly reconfigured. For Venter’s team, that included sequencing the genome of M. genitalium in 1995. Synthetic biology also includes “[b]ottom-up” research to create new organisms using only chemical reagents.Synthetic biology is used today in the field of assisted reproduction to analyze existing genes. An example of such “top-down” synthetic biology is preimplantation genetic diagnosis (“PGD”) to screen for human immunodeficiency virus, cystic fibrosis, or other diseases. This Article will focus on the “bottom-up” use of synthetic biology in the context of assisted reproduction. One day, scientists may be able to create synthetic human gametes or embryos for purposes of assisted reproduction. It is impossible to forecast when this may occur; as the 2010 Presidential Commission for the Study of Bioethical Issues noted, “the pace of discovery is unpredictable.” But instead of deferring the discussion until synthetic sperm or ova actually appear, we should anticipate the risks and benefits now. This Article will focus on the practical and regulatory issues that may encourage or inhibit the use of Venter’s technology to create synthetic gametes and the legal issues of parentage and inheritance for a synthetically created child.Part II of this Article sets the stage by briefly discussing infertility in the United States, the development of assisted reproduction technologies to counteract infertility, and other additional uses of assisted reproductive technologies (“ART”) such as PGD, which is also used by fertile couples. Part III examines the existing laws and regulations that may apply to the development of synthetic human gametes or embryos. With the market demands from Part II and the regulatory structure from Part III in mind, Part IV will look at the parentage and inheritance issues if a synthetic gamete results in a living child. Part V concludes the Article by exploring two approaches to regulatory issues." @default.
• W2104602109 created "2016-06-24" @default.
• W2104602109 creator A5032796629 @default.
• W2104602109 date "2011-09-01" @default.
• W2104602109 modified "2023-09-26" @default.
• W2104602109 title "Synthetic Cells, Synthetic Life, and Inheritance" @default.
• W2104602109 hasPublicationYear "2011" @default.
• W2104602109 type Work @default.
• W2104602109 sameAs 2104602109 @default.
• W2104602109 citedByCount "0" @default.
• W2104602109 crossrefType "posted-content" @default.
• W2104602109 hasAuthorship W2104602109A5032796629 @default.
• W2104602109 hasConcept C104317684 @default.
• W2104602109 hasConcept C141231307 @default.
• W2104602109 hasConcept C159047783 @default.
• W2104602109 hasConcept C191908910 @default.
• W2104602109 hasConcept C2777391075 @default.
• W2104602109 hasConcept C2780062933 @default.
• W2104602109 hasConcept C54355233 @default.
• W2104602109 hasConcept C70721500 @default.
• W2104602109 hasConcept C86803240 @default.
• W2104602109 hasConceptScore W2104602109C104317684 @default.
• W2104602109 hasConceptScore W2104602109C141231307 @default.
• W2104602109 hasConceptScore W2104602109C159047783 @default.
• W2104602109 hasConceptScore W2104602109C191908910 @default.
• W2104602109 hasConceptScore W2104602109C2777391075 @default.
• W2104602109 hasConceptScore W2104602109C2780062933 @default.
• W2104602109 hasConceptScore W2104602109C54355233 @default.
• W2104602109 hasConceptScore W2104602109C70721500 @default.
• W2104602109 hasConceptScore W2104602109C86803240 @default.
• W2104602109 hasLocation W21046021091 @default.
• W2104602109 hasOpenAccess W2104602109 @default.
• W2104602109 hasPrimaryLocation W21046021091 @default.
• W2104602109 hasRelatedWork W1547826601 @default.
• W2104602109 hasRelatedWork W1595848514 @default.
• W2104602109 hasRelatedWork W1611842248 @default.
• W2104602109 hasRelatedWork W1931054791 @default.
• W2104602109 hasRelatedWork W1970881235 @default.
• W2104602109 hasRelatedWork W1988376208 @default.
• W2104602109 hasRelatedWork W1990228532 @default.
• W2104602109 hasRelatedWork W1998247277 @default.
• W2104602109 hasRelatedWork W2021418319 @default.
• W2104602109 hasRelatedWork W2042631982 @default.
• W2104602109 hasRelatedWork W2101970300 @default.
• W2104602109 hasRelatedWork W2205020977 @default.
• W2104602109 hasRelatedWork W2271650037 @default.
• W2104602109 hasRelatedWork W2306228451 @default.
• W2104602109 hasRelatedWork W2740398346 @default.
• W2104602109 hasRelatedWork W3043108217 @default.
• W2104602109 hasRelatedWork W3150080187 @default.
• W2104602109 hasRelatedWork W94376326 @default.
• W2104602109 hasRelatedWork W155911118 @default.
• W2104602109 hasRelatedWork W2196997775 @default.
• W2104602109 isParatext "false" @default.
• W2104602109 isRetracted "false" @default.
• W2104602109 magId "2104602109" @default.
• W2104602109 workType "article" @default.