Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104635909> ?p ?o ?g. }
- W2104635909 endingPage "219" @default.
- W2104635909 startingPage "213" @default.
- W2104635909 abstract "Background. Bacterial vaginosis (BV) is the most common cause of vaginitis worldwide. Currently recommended treatments have poor efficacy and are associated with high rates of BV recurrence. We examined whether a longer duration of treatment with metronidazole or combination therapy with metronidazole and azithromycin would enhance the cure rates for BV. In addition, we examined factors other than drug therapy associated with cure. Methods. Women with symptomatic BV (defined by a modified Amsel criteria) were enrolled in a 4-arm study that compared metronidazole for 7 days versus 14 days, plus or minus azithromycin on days 1 and 3. Data regarding interim behaviors were also obtained, as were vaginal specimens for Gram staining. Results. At the first follow-up visit (7 days after the completion of therapy), there was a significant difference in cure rates among patients who received 7 days of metronidazole therapy, compared with those who received 14 days of therapy, combined across azithromycin therapy (P = .0003). There was no effect associated with azithromycin therapy. There were no differences in cure rates between any of the treatment groups at 21 days after completion of therapy. Abstinence or protected sex, refraining from douching, and a lower baseline Nugent score for the vaginal Gram stain were all significantly associated with cure. Conclusions. Cure rates for BV were significantly improved by 14 days of metronidazole treatment (compared with 7 days of treatment), but the effects were not sustained, suggesting that relapse or reinfection occurred. Combination therapy with the addition of azithromycin had no benefit. Lower baseline Nugent scores—presumably reflecting less complex vaginal flora—were significantly associated with cure, as was refraining from unprotected sex and from douching." @default.
- W2104635909 created "2016-06-24" @default.
- W2104635909 creator A5025156995 @default.
- W2104635909 creator A5037473242 @default.
- W2104635909 date "2007-01-15" @default.
- W2104635909 modified "2023-10-17" @default.
- W2104635909 title "A Randomized Trial of the Duration of Therapy with Metronidazole plus or minus Azithromycin for Treatment of Symptomatic Bacterial Vaginosis" @default.
- W2104635909 cites W1511490662 @default.
- W2104635909 cites W1856671815 @default.
- W2104635909 cites W1868667984 @default.
- W2104635909 cites W1990639292 @default.
- W2104635909 cites W2006148788 @default.
- W2104635909 cites W2009968817 @default.
- W2104635909 cites W2013981975 @default.
- W2104635909 cites W2020863493 @default.
- W2104635909 cites W2021799915 @default.
- W2104635909 cites W2042847766 @default.
- W2104635909 cites W2053052509 @default.
- W2104635909 cites W2053346041 @default.
- W2104635909 cites W2059574636 @default.
- W2104635909 cites W2059707463 @default.
- W2104635909 cites W2072388807 @default.
- W2104635909 cites W2072409597 @default.
- W2104635909 cites W2074729961 @default.
- W2104635909 cites W2090979248 @default.
- W2104635909 cites W2105504607 @default.
- W2104635909 cites W2112589439 @default.
- W2104635909 cites W2166200539 @default.
- W2104635909 cites W2317894502 @default.
- W2104635909 doi "https://doi.org/10.1086/509577" @default.
- W2104635909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17173219" @default.
- W2104635909 hasPublicationYear "2007" @default.
- W2104635909 type Work @default.
- W2104635909 sameAs 2104635909 @default.
- W2104635909 citedByCount "86" @default.
- W2104635909 countsByYear W21046359092012 @default.
- W2104635909 countsByYear W21046359092013 @default.
- W2104635909 countsByYear W21046359092014 @default.
- W2104635909 countsByYear W21046359092015 @default.
- W2104635909 countsByYear W21046359092016 @default.
- W2104635909 countsByYear W21046359092017 @default.
- W2104635909 countsByYear W21046359092018 @default.
- W2104635909 countsByYear W21046359092019 @default.
- W2104635909 countsByYear W21046359092020 @default.
- W2104635909 countsByYear W21046359092021 @default.
- W2104635909 countsByYear W21046359092022 @default.
- W2104635909 countsByYear W21046359092023 @default.
- W2104635909 crossrefType "journal-article" @default.
- W2104635909 hasAuthorship W2104635909A5025156995 @default.
- W2104635909 hasAuthorship W2104635909A5037473242 @default.
- W2104635909 hasBestOaLocation W21046359091 @default.
- W2104635909 hasConcept C126322002 @default.
- W2104635909 hasConcept C141071460 @default.
- W2104635909 hasConcept C168563851 @default.
- W2104635909 hasConcept C205501099 @default.
- W2104635909 hasConcept C2776999253 @default.
- W2104635909 hasConcept C2777396551 @default.
- W2104635909 hasConcept C2778907293 @default.
- W2104635909 hasConcept C2779952448 @default.
- W2104635909 hasConcept C2780626017 @default.
- W2104635909 hasConcept C29456083 @default.
- W2104635909 hasConcept C501593827 @default.
- W2104635909 hasConcept C71924100 @default.
- W2104635909 hasConcept C86803240 @default.
- W2104635909 hasConcept C89423630 @default.
- W2104635909 hasConceptScore W2104635909C126322002 @default.
- W2104635909 hasConceptScore W2104635909C141071460 @default.
- W2104635909 hasConceptScore W2104635909C168563851 @default.
- W2104635909 hasConceptScore W2104635909C205501099 @default.
- W2104635909 hasConceptScore W2104635909C2776999253 @default.
- W2104635909 hasConceptScore W2104635909C2777396551 @default.
- W2104635909 hasConceptScore W2104635909C2778907293 @default.
- W2104635909 hasConceptScore W2104635909C2779952448 @default.
- W2104635909 hasConceptScore W2104635909C2780626017 @default.
- W2104635909 hasConceptScore W2104635909C29456083 @default.
- W2104635909 hasConceptScore W2104635909C501593827 @default.
- W2104635909 hasConceptScore W2104635909C71924100 @default.
- W2104635909 hasConceptScore W2104635909C86803240 @default.
- W2104635909 hasConceptScore W2104635909C89423630 @default.
- W2104635909 hasIssue "2" @default.
- W2104635909 hasLocation W21046359091 @default.
- W2104635909 hasLocation W21046359092 @default.
- W2104635909 hasOpenAccess W2104635909 @default.
- W2104635909 hasPrimaryLocation W21046359091 @default.
- W2104635909 hasRelatedWork W1455626080 @default.
- W2104635909 hasRelatedWork W1991214621 @default.
- W2104635909 hasRelatedWork W2000167914 @default.
- W2104635909 hasRelatedWork W2104635909 @default.
- W2104635909 hasRelatedWork W2364737455 @default.
- W2104635909 hasRelatedWork W2417193877 @default.
- W2104635909 hasRelatedWork W2471200600 @default.
- W2104635909 hasRelatedWork W2780989098 @default.
- W2104635909 hasRelatedWork W4250018139 @default.
- W2104635909 hasRelatedWork W2736338747 @default.
- W2104635909 hasVolume "44" @default.
- W2104635909 isParatext "false" @default.
- W2104635909 isRetracted "false" @default.
- W2104635909 magId "2104635909" @default.