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• W2104679804 abstract "The brain of teleost fish exhibits a significant degree of sexual plasticity, even in adulthood. This unique feature is almost certainly attributable to a teleost-specific sexual differentiation process of the brain, which remains largely unknown. To dissect the molecular basis of sexual differentiation of the teleost brain, we searched for genes differentially expressed between both sexes in the medaka brain. One gene identified in the screen, cyp19a1b, which encodes the steroidogenic enzyme aromatase, was selected for further analysis. As opposed to the situation in most vertebrates, medaka cyp19a1b is expressed at higher levels in the adult female brain than the male brain. The female-biased expression in the brain is consistent regardless of reproductive or diurnal cycle. Medaka cyp19a1b is expressed throughout the ventricular zones in wide areas of the brain, where, in most regions, females have a greater degree of expression compared to males, with the optic tectum exhibiting the most conspicuous predominance in females. Contrary to what is known in mammals, cyp19a1b expression exhibits neither a transient elevation nor a sex difference in medaka embryos. It is not until just before the onset of puberty that cyp19a1b expression in the medaka brain is sexually differentiated. Finally, cyp19a1b expression in the medaka brain is not under the direct control of sex chromosome genes but relies mostly, if not solely, on oestrogen derived from the gonad. These unique properties of aromatase expression in the brain probably contribute substantially to the less rigid sexual differentiation process, thus ensuring remarkable sexual plasticity in the teleost brain." @default.
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• W2104679804 date "2011-04-11" @default.
• W2104679804 modified "2023-10-03" @default.
• W2104679804 title "Sex Differences in Aromatase Gene Expression in the Medaka Brain" @default.
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• W2104679804 cites W1963951882 @default.
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• W2104679804 cites W1969311370 @default.
• W2104679804 cites W1974337154 @default.
• W2104679804 cites W1978641783 @default.
• W2104679804 cites W1980932987 @default.
• W2104679804 cites W1981752185 @default.
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• W2104679804 cites W1998090234 @default.
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• W2104679804 cites W2005006458 @default.
• W2104679804 cites W2008061469 @default.
• W2104679804 cites W2009545059 @default.
• W2104679804 cites W2012472440 @default.
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• W2104679804 cites W2030025420 @default.
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• W2104679804 doi "https://doi.org/10.1111/j.1365-2826.2011.02120.x" @default.
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