FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104838175> ?p ?o ?g. }

• W2104838175 endingPage "121" @default.
• W2104838175 startingPage "113" @default.
• W2104838175 abstract "A growing body of evidence suggests that vasopressinergic activity in the hypothalamus is important in stress-related behaviors (like drug abuse) in line with a role in the regulation of the hypothalamo-pituitary–adrenal axis (HPA). We hypothesized that in the naturally vasopressin-deficient Brattleboro rat, acute and chronic morphine treatment may lead to reduced HPA axis activity. Rats were treated either with a single dose of morphine (10 mg/kg subcutaneously) and serial blood samples were taken or were treated twice daily with increasing doses of morphine (10–100 mg/kg subcutaneously) for 16 days and animals were killed by decapitation 4 or 16 h after the last injection. Single morphine injection induced a biphasic ACTH and corticosterone elevation with smaller increases in vasopressin-deficient rats. Chronic morphine treatment induced the typical somatic and HPA axis changes of chronic stress; the absence of vasopressin did not prevent these changes. In rats repeatedly treated with morphine plasma, ACTH and corticosterone levels were elevated both 4 and 16 h after the last injection (short and long withdrawal) and the absence of vasopressin attenuated this response. Our data suggest that vasopressin plays a prominent role in morphine treatment and withdrawal-induced acute hormonal changes, but does not affect development of chronic hyperactivity of the HPA axis." @default.
• W2104838175 created "2016-06-24" @default.
• W2104838175 creator A5029012043 @default.
• W2104838175 creator A5036621851 @default.
• W2104838175 creator A5044651066 @default.
• W2104838175 creator A5071692670 @default.
• W2104838175 creator A5083154152 @default.
• W2104838175 date "2007-10-16" @default.
• W2104838175 modified "2023-10-18" @default.
• W2104838175 title "Congenital vasopressin deficiency and acute and chronic opiate effects on hypothalamo-pituitary–adrenal axis activity in Brattleboro rats" @default.
• W2104838175 cites W1485094869 @default.
• W2104838175 cites W1537397940 @default.
• W2104838175 cites W1568579816 @default.
• W2104838175 cites W1969606885 @default.
• W2104838175 cites W1969764242 @default.
• W2104838175 cites W1971711780 @default.
• W2104838175 cites W1976027570 @default.
• W2104838175 cites W1981333355 @default.
• W2104838175 cites W2000031660 @default.
• W2104838175 cites W2009415328 @default.
• W2104838175 cites W2011477714 @default.
• W2104838175 cites W2019571241 @default.
• W2104838175 cites W2019641811 @default.
• W2104838175 cites W2024941992 @default.
• W2104838175 cites W2027002868 @default.
• W2104838175 cites W2031934304 @default.
• W2104838175 cites W2038222018 @default.
• W2104838175 cites W2044068453 @default.
• W2104838175 cites W2046442755 @default.
• W2104838175 cites W2054062157 @default.
• W2104838175 cites W2059938655 @default.
• W2104838175 cites W2064159242 @default.
• W2104838175 cites W2079718962 @default.
• W2104838175 cites W2113739957 @default.
• W2104838175 cites W2124243407 @default.
• W2104838175 cites W2126792672 @default.
• W2104838175 cites W2133388811 @default.
• W2104838175 cites W2143772921 @default.
• W2104838175 cites W2157533576 @default.
• W2104838175 cites W2167234436 @default.
• W2104838175 cites W2214956132 @default.
• W2104838175 cites W2537548100 @default.
• W2104838175 doi "https://doi.org/10.1677/joe-07-0356" @default.
• W2104838175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18180322" @default.
• W2104838175 hasPublicationYear "2007" @default.
• W2104838175 type Work @default.
• W2104838175 sameAs 2104838175 @default.
• W2104838175 citedByCount "19" @default.
• W2104838175 countsByYear W21048381752012 @default.
• W2104838175 countsByYear W21048381752013 @default.
• W2104838175 countsByYear W21048381752015 @default.
• W2104838175 countsByYear W21048381752020 @default.
• W2104838175 countsByYear W21048381752021 @default.
• W2104838175 countsByYear W21048381752023 @default.
• W2104838175 crossrefType "journal-article" @default.
• W2104838175 hasAuthorship W2104838175A5029012043 @default.
• W2104838175 hasAuthorship W2104838175A5036621851 @default.
• W2104838175 hasAuthorship W2104838175A5044651066 @default.
• W2104838175 hasAuthorship W2104838175A5071692670 @default.
• W2104838175 hasAuthorship W2104838175A5083154152 @default.
• W2104838175 hasBestOaLocation W21048381751 @default.
• W2104838175 hasConcept C118303440 @default.
• W2104838175 hasConcept C126322002 @default.
• W2104838175 hasConcept C134018914 @default.
• W2104838175 hasConcept C170493617 @default.
• W2104838175 hasConcept C2776370428 @default.
• W2104838175 hasConcept C2777003273 @default.
• W2104838175 hasConcept C2777389121 @default.
• W2104838175 hasConcept C2778140631 @default.
• W2104838175 hasConcept C2779146795 @default.
• W2104838175 hasConcept C2780352252 @default.
• W2104838175 hasConcept C71315377 @default.
• W2104838175 hasConcept C71924100 @default.
• W2104838175 hasConceptScore W2104838175C118303440 @default.
• W2104838175 hasConceptScore W2104838175C126322002 @default.
• W2104838175 hasConceptScore W2104838175C134018914 @default.
• W2104838175 hasConceptScore W2104838175C170493617 @default.
• W2104838175 hasConceptScore W2104838175C2776370428 @default.
• W2104838175 hasConceptScore W2104838175C2777003273 @default.
• W2104838175 hasConceptScore W2104838175C2777389121 @default.
• W2104838175 hasConceptScore W2104838175C2778140631 @default.
• W2104838175 hasConceptScore W2104838175C2779146795 @default.
• W2104838175 hasConceptScore W2104838175C2780352252 @default.
• W2104838175 hasConceptScore W2104838175C71315377 @default.
• W2104838175 hasConceptScore W2104838175C71924100 @default.
• W2104838175 hasIssue "1" @default.
• W2104838175 hasLocation W21048381751 @default.
• W2104838175 hasLocation W21048381752 @default.
• W2104838175 hasOpenAccess W2104838175 @default.
• W2104838175 hasPrimaryLocation W21048381751 @default.
• W2104838175 hasRelatedWork W1939585081 @default.
• W2104838175 hasRelatedWork W1964318160 @default.
• W2104838175 hasRelatedWork W1966015575 @default.
• W2104838175 hasRelatedWork W1986331805 @default.
• W2104838175 hasRelatedWork W2074358091 @default.
• W2104838175 hasRelatedWork W2094511447 @default.
• W2104838175 hasRelatedWork W2096219287 @default.
• W2104838175 hasRelatedWork W2104452243 @default.

• next