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- W2104883907 abstract "A three-month open, multicentre trial was carried out in 2132 hypertensive patients under uncontrolled conditions in general practice, to assess the effectiveness and tolerance of acebutolol when given orally as a single morning dose, in the range of 200 to 1200 mg/day. Concomitant antihypertensive therapy was given to 702 patients. Forty-five patients, out of 1893 who were eligible for analysis, showed inadequate blood pressure control and were withdrawn from the study. There were 602 reports of side-effects or adverse reactions attributed to acebutolol in 584 patients, necessitating 120 withdrawals from the trial. The results showed that acebutolol given once daily produces a substantial and progressive reduction in blood pressure over the three months of the trial. The changes from pre-trial values of all haemodynamic assessments measured were statistically significant (p < 0-001)." @default.
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- W2104883907 date "1979-05-01" @default.
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- W2104883907 title "A Multicentre Study of a Once Daily Dosage of Acebutolol* in the Treatment of Hypertension in General Practice" @default.
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- W2104883907 doi "https://doi.org/10.1177/030006057900700307" @default.
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