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• W2104921957 abstract "Summary Useful pharmacoeconomic data can be derivedfrom RCTs and observational studies. There is,however, no single pharmacoeconomic study thatwill establish the value of an intervention. Differ-ent audiences bring a variety of perspectives, aswell as definitions of value, to the generation,framing, and interpretation of research questions.Establishing value can result from the synthesis ofdata from a variety of sources, including RCTs,observational studies, and modeling, with appro-priate attention to the weaknesses and limitationsof each kind of data.The most important factors for a researcher toconsider in designing a clinical trial to answerquestions of value are knowing the precise ques-tion(s) that the study is required to answer andknowing the informational needs of the target au-dience. Over the long term, it is recommendedthat effort be directed towards better consensusand a greater degree of standardization of defini-tions and methodologies for assessing health eco-nomic questions through clinical studies." @default.
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• W2104921957 date "1999-03-01" @default.
• W2104921957 modified "2023-09-30" @default.
• W2104921957 title "Panel 1: Methodological Issues in Pharmacoeconomic Evaluations—Clinical Studies" @default.
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• W2104921957 doi "https://doi.org/10.1046/j.1524-4733.1999.02202.x" @default.
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