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• W2104927376 abstract "Pulmonary surfactant forms a lipid-rich monolayer that coats the airways of the lung and is essential for proper inflation and function of the lung. Surfactant is produced by alveolar type II cells, stored intracellularly in organelles known as lamellar bodies, and secreted by exocytosis. The gene for ATP-binding cassette transporter A3 (ABCA3) is expressed in alveolar type II cells, and the protein is localized to lamellar bodies, suggesting that it has an important role in surfactant metabolism." @default.
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• W2104927376 date "2004-03-25" @default.
• W2104927376 modified "2023-10-18" @default.
• W2104927376 title "<i>ABCA3</i>Gene Mutations in Newborns with Fatal Surfactant Deficiency" @default.
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• W2104927376 doi "https://doi.org/10.1056/nejmoa032178" @default.
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