Matches in SemOpenAlex for { <https://semopenalex.org/work/W2104946987> ?p ?o ?g. }
- W2104946987 abstract "The basic tenets of germ cell development are conserved among metazoans. Following lineage commitment in the embryo, germ cells proliferate, transition into meiosis, and then differentiate into gametes capable of fertilization. In lower organisms such as Drosophila and C. elegans, germline stem cells make the decision to proliferate or enter meiosis based in large part on the regulated expression of genes by translational control. This study undertakes a direct characterization of mRNAs that experience translational control and their involvement in similar decisions in the mammalian testis. We previously showed that translation of mRNA encoding the germ cell-specific gene Rhox13 was suppressed in the fetal and neonatal testis. By investigating changes in message utilization during neonatal testis development, we found that a large number of mRNAs encoding both housekeeping and germ cell-specific proteins experience enhanced translational efficiency, rather than increase in abundance, in the testis as quiescent gonocytes transition to mitotic spermatogonia. Our results indicate that translational control is a significant regulator of the germ cell proteome during neonatal testis development." @default.
- W2104946987 created "2016-06-24" @default.
- W2104946987 creator A5023664100 @default.
- W2104946987 creator A5039017930 @default.
- W2104946987 creator A5064434213 @default.
- W2104946987 creator A5079886250 @default.
- W2104946987 date "2013-09-01" @default.
- W2104946987 modified "2023-09-24" @default.
- W2104946987 title "Translational Activation of Developmental Messenger RNAs During Neonatal Mouse Testis Development1" @default.
- W2104946987 cites W1528634627 @default.
- W2104946987 cites W1645470992 @default.
- W2104946987 cites W1886173260 @default.
- W2104946987 cites W1964628768 @default.
- W2104946987 cites W1966150502 @default.
- W2104946987 cites W1979072418 @default.
- W2104946987 cites W1980084095 @default.
- W2104946987 cites W1983713993 @default.
- W2104946987 cites W1985126774 @default.
- W2104946987 cites W1986257122 @default.
- W2104946987 cites W1997444723 @default.
- W2104946987 cites W1999183933 @default.
- W2104946987 cites W2004608668 @default.
- W2104946987 cites W2005673370 @default.
- W2104946987 cites W2013096494 @default.
- W2104946987 cites W2015729941 @default.
- W2104946987 cites W2018384224 @default.
- W2104946987 cites W2020234109 @default.
- W2104946987 cites W2021569885 @default.
- W2104946987 cites W2036573675 @default.
- W2104946987 cites W2036760181 @default.
- W2104946987 cites W2038752568 @default.
- W2104946987 cites W2045830695 @default.
- W2104946987 cites W2048136762 @default.
- W2104946987 cites W2057185316 @default.
- W2104946987 cites W2057844875 @default.
- W2104946987 cites W2060676189 @default.
- W2104946987 cites W2071709406 @default.
- W2104946987 cites W2078337444 @default.
- W2104946987 cites W2081485874 @default.
- W2104946987 cites W2084521437 @default.
- W2104946987 cites W2092038323 @default.
- W2104946987 cites W2098085839 @default.
- W2104946987 cites W2105097906 @default.
- W2104946987 cites W2111030565 @default.
- W2104946987 cites W2113083989 @default.
- W2104946987 cites W2116472345 @default.
- W2104946987 cites W2116989098 @default.
- W2104946987 cites W2120027567 @default.
- W2104946987 cites W2120865735 @default.
- W2104946987 cites W2128551987 @default.
- W2104946987 cites W2133058137 @default.
- W2104946987 cites W2133482368 @default.
- W2104946987 cites W2133948311 @default.
- W2104946987 cites W2142048498 @default.
- W2104946987 cites W2143023822 @default.
- W2104946987 cites W2154465060 @default.
- W2104946987 cites W2158990581 @default.
- W2104946987 cites W2159586874 @default.
- W2104946987 cites W2169345822 @default.
- W2104946987 doi "https://doi.org/10.1095/biolreprod.113.109819" @default.
- W2104946987 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4094195" @default.
- W2104946987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23926285" @default.
- W2104946987 hasPublicationYear "2013" @default.
- W2104946987 type Work @default.
- W2104946987 sameAs 2104946987 @default.
- W2104946987 citedByCount "20" @default.
- W2104946987 countsByYear W21049469872014 @default.
- W2104946987 countsByYear W21049469872015 @default.
- W2104946987 countsByYear W21049469872016 @default.
- W2104946987 countsByYear W21049469872017 @default.
- W2104946987 countsByYear W21049469872018 @default.
- W2104946987 countsByYear W21049469872019 @default.
- W2104946987 countsByYear W21049469872022 @default.
- W2104946987 crossrefType "journal-article" @default.
- W2104946987 hasAuthorship W2104946987A5023664100 @default.
- W2104946987 hasAuthorship W2104946987A5039017930 @default.
- W2104946987 hasAuthorship W2104946987A5064434213 @default.
- W2104946987 hasAuthorship W2104946987A5079886250 @default.
- W2104946987 hasBestOaLocation W21049469871 @default.
- W2104946987 hasConcept C104317684 @default.
- W2104946987 hasConcept C105580179 @default.
- W2104946987 hasConcept C109825262 @default.
- W2104946987 hasConcept C148196450 @default.
- W2104946987 hasConcept C149364088 @default.
- W2104946987 hasConcept C150194340 @default.
- W2104946987 hasConcept C190446060 @default.
- W2104946987 hasConcept C196843134 @default.
- W2104946987 hasConcept C2775992057 @default.
- W2104946987 hasConcept C2779122487 @default.
- W2104946987 hasConcept C33922130 @default.
- W2104946987 hasConcept C39685955 @default.
- W2104946987 hasConcept C54355233 @default.
- W2104946987 hasConcept C84298646 @default.
- W2104946987 hasConcept C86803240 @default.
- W2104946987 hasConcept C93304396 @default.
- W2104946987 hasConcept C95444343 @default.
- W2104946987 hasConceptScore W2104946987C104317684 @default.
- W2104946987 hasConceptScore W2104946987C105580179 @default.
- W2104946987 hasConceptScore W2104946987C109825262 @default.
- W2104946987 hasConceptScore W2104946987C148196450 @default.