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• W2104964319 abstract "The development of obligate fungal parasites on their host plants is controlled by genes for resistance in the host and genes for virulence in the pathogen (30). Analyses by techniques of classical genetics have led to the concept of the gene-for­ gene relationship (25, 30, 52), which accounts for the striking degree of varietal specificity exhibited by the physiological races of phytopathogenic fungi such as the rusts and powdery mildews. While this concept has been useful in investigations concerning the nature of disease resistance in terms of Mendelian genetics (31, 52), the molecular basis of the action of specific resistance genes in determining the outcome of host parasite interactions is far from clear. Infection of higher plants by fungal pathogens is accompanied by major changes in the metabolism of the host. These metabolic transitions have often been correlated with the appearance of new isozymes or enzymes with altered properties (66, 69). Therefore, host-parasite interactions that lead to susceptibility or resistance of a host plant to a pathogen are likely to take place at a very early stage--during transcrip­ tion and translation. During the last five years, remarkable progress has been achieved toward under­ standing the mechanism of eucaryotic gene expression. The transcription of DNA into RNA in plants, animals, and fungi is controlled by two mechanisms: (a) template activity of chromatin as determined by the structure and arrangement of chromosomal proteins (33, 76) and (b) the transcriptive specificity of the multiple molecular forms of RNA polymerase (5, 27). Furthermore, gene expression is now known to be regulated during both transcriptional and post-transcriptional process­ ing (5, 9, 22) of all classes of precursor RNA into biologically active ribosomal RNA" @default.
• W2104964319 created "2016-06-24" @default.
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• W2104964319 date "1977-09-01" @default.
• W2104964319 modified "2023-09-23" @default.
• W2104964319 title "The Role of RNA in Host-Parasite Specificity" @default.
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• W2104964319 doi "https://doi.org/10.1146/annurev.py.15.090177.001031" @default.
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