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- W2104996959 abstract "days (Caldwell, Mazer & Wright, 1967). These authors also reported that transplanting rat uteri to the cheek pouch also reduced pseudopregnancy in hysterectomized hamsters (14m=.8days), whereas the effects of transplanting rabbit uteri (15m=.5days) were not as conclusive. Human endometrium had no apparent shortening influence on the pseudopregnancy cycle length (17m=.5days). These results suggested that the regulatory effect of the uterus on the life span of corpora lutea may not be species specific and the present study was initiated to investigate the influence of sheep endometrium and endometrial preparations on the length of copulation-induced pseudopregnancy in hysterectomized hamsters. Previous studies on sheep (Wiltbank & Casida, 1956; Moor & Rowson, 1964) showed that hysterectomy prolongs the life span of corpora lutea to 145 days and recent experiments have established that autotransplantation of endometrium significantly reduces this extended period to 35 to 40 days (Rowson, Moor, Hay & Caldwell, unpublished). Mature female hamsters weighing between 85 and 125 g were totally hysterectomized under Nembutal (8 mg/100 g body wt) and allowed 6 to 10 days as a post-operative recovery period. Fertile males were then placed with the individually caged animals and the females observed for signs of oestrus (lordosis). At least one normal 4-day oestrous cycle was recorded before mating was permitted to occur and the resulting length of pseudopregnancy was taken to be the same as the period before the appearance of the next oestrus. Sheep endometrium was stripped from the myometrium and cut into small pieces before being inserted between the inner membranes of the hamster cheek pouch as previously described for other tissue (Caldwell, Pawling & Wright," @default.
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- W2104996959 date "1968-12-01" @default.
- W2104996959 modified "2023-09-23" @default.
- W2104996959 title "EFFECTS OF SHEEP ENDOMETRIAL GRAFTS AND EXTRACTS ON THE LENGTH OF PSEUDOPREGNANCY IN THE HYSTERECTOMIZED HAMSTER" @default.
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- W2104996959 doi "https://doi.org/10.1530/jrf.0.0170567" @default.
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