FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105060097> ?p ?o ?g. }

• W2105060097 endingPage "1094" @default.
• W2105060097 startingPage "1086" @default.
• W2105060097 abstract "The aim of this study was to test the contribution of anti-myelin antibodies in predicting conversion from clinically isolated syndrome (CIS) to multiple sclerosis (MS) when considering either Poser's or McDonald's diagnostic criteria. Fifty-one patients with CIS and abnormal brain MRI were imaged monthly for six months and then at 12, 18, 24, 36 months. At baseline serum samples testing antibodies against myelin oligodendrocyte glycoprotein (anti-MOG) and myelin basic protein (anti-MBP) were collected. During the 36-month follow-up, 26 (51%) patients developed a relapse thus becoming clinically definite MS (CDMS) according to Poser's criteria; 46 (90.2%) patients converted to MS according to McDonald's criteria. Out of 51 patients, 28 (54.9%) had either double or single positivity for anti-myelin antibodies. Antibody status significantly predicted MS according to Poser's criteria (P=0.004), but did not according to the McDonald's criteria. When compared to antibody negative patients, the risk of developing a relapse was 8.9 (95% CI: 2.7-29.8; P<0.001) for anti-MBP positive (anti-MBP+) patients and 1.5 (95% CI: 0.4-5.4; P=0.564) for those anti-MOG positive (anti-MOG+); double positive patients (ie, anti-MBP+/anti-MOG+) had a risk of relapse's occurrence equal to 3.4 (95% CI: 1.1-10.2; P=0.031). Also, the antibody status predicted the median time span from CIS to CDMS, that was of 36 months in the anti-MOG-/anti-MBP- group, 33 months in the anti-MOG+/anti-MBP- group, 24 months in the anti-MOG+/anti-MBP+ group and 12 months in the anti-MOG-/anti-MBP+ patients (P=0.003 by ANOVA). Our data support the prognostic value of anti-myelin antibodies in CIS patients at risk of CDMS, with positive patients showing shorter time interval to relapse occurrence than negative patients." @default.
• W2105060097 created "2016-06-24" @default.
• W2105060097 creator A5039146680 @default.
• W2105060097 creator A5042027191 @default.
• W2105060097 creator A5050367507 @default.
• W2105060097 creator A5060017986 @default.
• W2105060097 creator A5060641186 @default.
• W2105060097 creator A5063199948 @default.
• W2105060097 creator A5075335015 @default.
• W2105060097 creator A5083385630 @default.
• W2105060097 date "2007-04-27" @default.
• W2105060097 modified "2023-09-27" @default.
• W2105060097 title "Anti-myelin antibodies predict the clinical outcome after a first episode suggestive of MS" @default.
• W2105060097 cites W1966515383 @default.
• W2105060097 cites W1973391024 @default.
• W2105060097 cites W1979998628 @default.
• W2105060097 cites W1985495387 @default.
• W2105060097 cites W2011595922 @default.
• W2105060097 cites W2025240311 @default.
• W2105060097 cites W2028435653 @default.
• W2105060097 cites W2037979244 @default.
• W2105060097 cites W2041543008 @default.
• W2105060097 cites W2044316391 @default.
• W2105060097 cites W2045762174 @default.
• W2105060097 cites W2047654165 @default.
• W2105060097 cites W2063788294 @default.
• W2105060097 cites W2066086210 @default.
• W2105060097 cites W2073960456 @default.
• W2105060097 cites W2074074558 @default.
• W2105060097 cites W2085252474 @default.
• W2105060097 cites W2095666175 @default.
• W2105060097 cites W2105026328 @default.
• W2105060097 cites W2105490558 @default.
• W2105060097 cites W2112165124 @default.
• W2105060097 cites W2122894564 @default.
• W2105060097 cites W2130355701 @default.
• W2105060097 cites W2132891287 @default.
• W2105060097 cites W2137350492 @default.
• W2105060097 cites W2150181574 @default.
• W2105060097 cites W2313649737 @default.
• W2105060097 cites W2325038063 @default.
• W2105060097 cites W2608367334 @default.
• W2105060097 doi "https://doi.org/10.1177/1352458507077622" @default.
• W2105060097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17468447" @default.
• W2105060097 hasPublicationYear "2007" @default.
• W2105060097 type Work @default.
• W2105060097 sameAs 2105060097 @default.
• W2105060097 citedByCount "51" @default.
• W2105060097 countsByYear W21050600972012 @default.
• W2105060097 countsByYear W21050600972013 @default.
• W2105060097 countsByYear W21050600972014 @default.
• W2105060097 countsByYear W21050600972015 @default.
• W2105060097 countsByYear W21050600972016 @default.
• W2105060097 countsByYear W21050600972017 @default.
• W2105060097 countsByYear W21050600972018 @default.
• W2105060097 countsByYear W21050600972019 @default.
• W2105060097 countsByYear W21050600972021 @default.
• W2105060097 countsByYear W21050600972022 @default.
• W2105060097 countsByYear W21050600972023 @default.
• W2105060097 crossrefType "journal-article" @default.
• W2105060097 hasAuthorship W2105060097A5039146680 @default.
• W2105060097 hasAuthorship W2105060097A5042027191 @default.
• W2105060097 hasAuthorship W2105060097A5050367507 @default.
• W2105060097 hasAuthorship W2105060097A5060017986 @default.
• W2105060097 hasAuthorship W2105060097A5060641186 @default.
• W2105060097 hasAuthorship W2105060097A5063199948 @default.
• W2105060097 hasAuthorship W2105060097A5075335015 @default.
• W2105060097 hasAuthorship W2105060097A5083385630 @default.
• W2105060097 hasConcept C126322002 @default.
• W2105060097 hasConcept C159654299 @default.
• W2105060097 hasConcept C187382586 @default.
• W2105060097 hasConcept C203014093 @default.
• W2105060097 hasConcept C2778486448 @default.
• W2105060097 hasConcept C2778609137 @default.
• W2105060097 hasConcept C2779357208 @default.
• W2105060097 hasConcept C2780640218 @default.
• W2105060097 hasConcept C2781028063 @default.
• W2105060097 hasConcept C529278444 @default.
• W2105060097 hasConcept C71924100 @default.
• W2105060097 hasConcept C90924648 @default.
• W2105060097 hasConceptScore W2105060097C126322002 @default.
• W2105060097 hasConceptScore W2105060097C159654299 @default.
• W2105060097 hasConceptScore W2105060097C187382586 @default.
• W2105060097 hasConceptScore W2105060097C203014093 @default.
• W2105060097 hasConceptScore W2105060097C2778486448 @default.
• W2105060097 hasConceptScore W2105060097C2778609137 @default.
• W2105060097 hasConceptScore W2105060097C2779357208 @default.
• W2105060097 hasConceptScore W2105060097C2780640218 @default.
• W2105060097 hasConceptScore W2105060097C2781028063 @default.
• W2105060097 hasConceptScore W2105060097C529278444 @default.
• W2105060097 hasConceptScore W2105060097C71924100 @default.
• W2105060097 hasConceptScore W2105060097C90924648 @default.
• W2105060097 hasIssue "9" @default.
• W2105060097 hasLocation W21050600971 @default.
• W2105060097 hasLocation W21050600972 @default.
• W2105060097 hasOpenAccess W2105060097 @default.
• W2105060097 hasPrimaryLocation W21050600971 @default.
• W2105060097 hasRelatedWork W2011247790 @default.

• next