FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105130257> ?p ?o ?g. }

• W2105130257 endingPage "456" @default.
• W2105130257 startingPage "451" @default.
• W2105130257 abstract "Staphylococcal γ-hemolysin and leukocidin are bi-component cytolysins, consisting of LukF (or Hlg1)/Hlg2 and LukF/LukS, respectively. Here, we purified serum inhibitors of γ-hemolysin and leukocidin from human plasma. Protein sequencing showed that the purified inhibitors of 62, 57, 50 and 38 kDa were the vitronectin fragments with truncation(s) of the C-terminal or both N- and C-terminal regions. The purified vitronectin fragments specifically bound to the Hlg2 component of γ-hemolysin and the LukS component of leukocidin to form high-molecular-weight complexes with them, leading to inhibition of the toxin-induced lysis of human erythrocytes and human polymorphonuclear leukocytes, respectively. Intact vitronectin also showed inhibitory activity to the toxins. The ability of γ-hemolysin and leukocidin to bind vitronectin and its fragments is a novel function of the pore-forming cytolysins." @default.
• W2105130257 created "2016-06-24" @default.
• W2105130257 creator A5000440139 @default.
• W2105130257 creator A5002716298 @default.
• W2105130257 creator A5038932731 @default.
• W2105130257 creator A5090216578 @default.
• W2105130257 date "1999-11-01" @default.
• W2105130257 modified "2023-09-26" @default.
• W2105130257 title "Vitronectin and its fragments purified as serum inhibitors ofStaphylococcus aureusγ-hemolysin and leukocidin, and their specific binding to the Hlg2 and the LukS components of the toxins" @default.
• W2105130257 cites W1479947925 @default.
• W2105130257 cites W1522673104 @default.
• W2105130257 cites W1875022849 @default.
• W2105130257 cites W1897911390 @default.
• W2105130257 cites W1913839795 @default.
• W2105130257 cites W1932052686 @default.
• W2105130257 cites W1963573942 @default.
• W2105130257 cites W1964171893 @default.
• W2105130257 cites W1981988806 @default.
• W2105130257 cites W1983116927 @default.
• W2105130257 cites W2016121744 @default.
• W2105130257 cites W2042568721 @default.
• W2105130257 cites W2066279385 @default.
• W2105130257 cites W2085191633 @default.
• W2105130257 cites W2093951251 @default.
• W2105130257 cites W2094252315 @default.
• W2105130257 cites W2100837269 @default.
• W2105130257 cites W2111301002 @default.
• W2105130257 cites W2147810945 @default.
• W2105130257 cites W2177719047 @default.
• W2105130257 cites W2231047350 @default.
• W2105130257 cites W2269547579 @default.
• W2105130257 cites W4293247451 @default.
• W2105130257 doi "https://doi.org/10.1016/s0014-5793(99)01376-9" @default.
• W2105130257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10556515" @default.
• W2105130257 hasPublicationYear "1999" @default.
• W2105130257 type Work @default.
• W2105130257 sameAs 2105130257 @default.
• W2105130257 citedByCount "5" @default.
• W2105130257 countsByYear W21051302572015 @default.
• W2105130257 countsByYear W21051302572017 @default.
• W2105130257 crossrefType "journal-article" @default.
• W2105130257 hasAuthorship W2105130257A5000440139 @default.
• W2105130257 hasAuthorship W2105130257A5002716298 @default.
• W2105130257 hasAuthorship W2105130257A5038932731 @default.
• W2105130257 hasAuthorship W2105130257A5090216578 @default.
• W2105130257 hasBestOaLocation W21051302571 @default.
• W2105130257 hasConcept C104317684 @default.
• W2105130257 hasConcept C136139683 @default.
• W2105130257 hasConcept C153911025 @default.
• W2105130257 hasConcept C164144092 @default.
• W2105130257 hasConcept C170493617 @default.
• W2105130257 hasConcept C185592680 @default.
• W2105130257 hasConcept C195687474 @default.
• W2105130257 hasConcept C203014093 @default.
• W2105130257 hasConcept C2777052132 @default.
• W2105130257 hasConcept C2777367657 @default.
• W2105130257 hasConcept C2777805791 @default.
• W2105130257 hasConcept C2779489039 @default.
• W2105130257 hasConcept C2779902561 @default.
• W2105130257 hasConcept C523546767 @default.
• W2105130257 hasConcept C54355233 @default.
• W2105130257 hasConcept C55493867 @default.
• W2105130257 hasConcept C60987743 @default.
• W2105130257 hasConcept C86803240 @default.
• W2105130257 hasConcept C89423630 @default.
• W2105130257 hasConceptScore W2105130257C104317684 @default.
• W2105130257 hasConceptScore W2105130257C136139683 @default.
• W2105130257 hasConceptScore W2105130257C153911025 @default.
• W2105130257 hasConceptScore W2105130257C164144092 @default.
• W2105130257 hasConceptScore W2105130257C170493617 @default.
• W2105130257 hasConceptScore W2105130257C185592680 @default.
• W2105130257 hasConceptScore W2105130257C195687474 @default.
• W2105130257 hasConceptScore W2105130257C203014093 @default.
• W2105130257 hasConceptScore W2105130257C2777052132 @default.
• W2105130257 hasConceptScore W2105130257C2777367657 @default.
• W2105130257 hasConceptScore W2105130257C2777805791 @default.
• W2105130257 hasConceptScore W2105130257C2779489039 @default.
• W2105130257 hasConceptScore W2105130257C2779902561 @default.
• W2105130257 hasConceptScore W2105130257C523546767 @default.
• W2105130257 hasConceptScore W2105130257C54355233 @default.
• W2105130257 hasConceptScore W2105130257C55493867 @default.
• W2105130257 hasConceptScore W2105130257C60987743 @default.
• W2105130257 hasConceptScore W2105130257C86803240 @default.
• W2105130257 hasConceptScore W2105130257C89423630 @default.
• W2105130257 hasIssue "3" @default.
• W2105130257 hasLocation W21051302571 @default.
• W2105130257 hasLocation W21051302572 @default.
• W2105130257 hasOpenAccess W2105130257 @default.
• W2105130257 hasPrimaryLocation W21051302571 @default.
• W2105130257 hasRelatedWork W2011657535 @default.
• W2105130257 hasRelatedWork W2024414727 @default.
• W2105130257 hasRelatedWork W2104829858 @default.
• W2105130257 hasRelatedWork W2123017648 @default.
• W2105130257 hasRelatedWork W2182584927 @default.
• W2105130257 hasRelatedWork W2348436109 @default.
• W2105130257 hasRelatedWork W2524668092 @default.
• W2105130257 hasRelatedWork W2555043369 @default.
• W2105130257 hasRelatedWork W2889312572 @default.

• next