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- W2105134580 abstract "ABSTRACT During Bacillus subtilis sporulation, the transient engulfment defect of spoIIB strains is enhanced by spoVG null mutations and suppressed by spoVS null mutations. These mutations have opposite effects on expression of the motility regulon, as the spoVG mutation reduces and the spoVS mutation increases σ D -directed gene expression, cell separation, and autolysis. Elevating σ D activity by eliminating the anti-σ factor FlgM also suppresses spoIIB spoVG , and both flgM and spoVS mutations cause continued expression of the σ D regulon during sporulation. We propose that peptidoglycan hydrolases induced during motility can substitute for sporulation-specific hydrolases during engulfment. We find that sporulating cells are heterogeneous in their expression of the motility regulon, which could result in phenotypic variation between individual sporulating cells." @default.
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- W2105134580 date "2006-02-01" @default.
- W2105134580 modified "2023-10-15" @default.
- W2105134580 title "Suppression of Engulfment Defects in <i>Bacillus subtilis</i> by Elevated Expression of the Motility Regulon" @default.
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- W2105134580 doi "https://doi.org/10.1128/jb.188.3.1159-1164.2006" @default.
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