Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105184098> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2105184098 endingPage "375" @default.
- W2105184098 startingPage "375" @default.
- W2105184098 abstract "<h3>Abstract</h3> During development, biological neural networks produce more synapses and neurons than needed. Many of these synapses and neurons are later removed in a process known as neural pruning. Why networks should initially be over-populated, and processes that determine which synapses and neurons are ultimately pruned, remains unclear. We study the mechanisms and significance of neural pruning in model neural network. In a deep Boltzmann machine model of sensory encoding, we find that (1) synaptic pruning is necessary to learn efficient network architectures that retain computationally-relevant connections, (2) pruning by synaptic weight alone does not optimize network size and (3) pruning based on a locally-available proxy for “sloppiness” based on Fisher Information allows the network to identify structurally important vs. unimportant connections and neurons. This locally-available measure of importance has a biological interpretation in terms of the correlations between presynaptic and postsynaptic neurons, and implies an efficient activity-driven pruning rule. Overall, we show how local activity-dependent synaptic pruning can solve the global problem of optimizing a network architecture. We relate these findings to biology as follows: (I) Synaptic over-production is necessary for activity-dependent connectivity optimization. (II) In networks that have more neurons than needed, cells compete for activity, and only the most important and selective neurons are retained. (III) Cells may also be pruned due to a loss of synapses on their axons. This occurs when the information they convey is not relevant to the target population." @default.
- W2105184098 created "2016-06-24" @default.
- W2105184098 creator A5003365317 @default.
- W2105184098 creator A5012687782 @default.
- W2105184098 creator A5036301763 @default.
- W2105184098 creator A5042005266 @default.
- W2105184098 creator A5058415159 @default.
- W2105184098 creator A5067049664 @default.
- W2105184098 creator A5074068858 @default.
- W2105184098 creator A5091860051 @default.
- W2105184098 date "1995-04-01" @default.
- W2105184098 modified "2023-10-06" @default.
- W2105184098 title "How many inpatient paediatric units do we need?" @default.
- W2105184098 cites W3139653071 @default.
- W2105184098 doi "https://doi.org/10.1136/adc.72.4.375" @default.
- W2105184098 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1511252" @default.
- W2105184098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7763078" @default.
- W2105184098 hasPublicationYear "1995" @default.
- W2105184098 type Work @default.
- W2105184098 sameAs 2105184098 @default.
- W2105184098 citedByCount "0" @default.
- W2105184098 crossrefType "journal-article" @default.
- W2105184098 hasAuthorship W2105184098A5003365317 @default.
- W2105184098 hasAuthorship W2105184098A5012687782 @default.
- W2105184098 hasAuthorship W2105184098A5036301763 @default.
- W2105184098 hasAuthorship W2105184098A5042005266 @default.
- W2105184098 hasAuthorship W2105184098A5058415159 @default.
- W2105184098 hasAuthorship W2105184098A5067049664 @default.
- W2105184098 hasAuthorship W2105184098A5074068858 @default.
- W2105184098 hasAuthorship W2105184098A5091860051 @default.
- W2105184098 hasBestOaLocation W21051840981 @default.
- W2105184098 hasConcept C108010975 @default.
- W2105184098 hasConcept C118403218 @default.
- W2105184098 hasConcept C119857082 @default.
- W2105184098 hasConcept C126322002 @default.
- W2105184098 hasConcept C154945302 @default.
- W2105184098 hasConcept C169760540 @default.
- W2105184098 hasConcept C170493617 @default.
- W2105184098 hasConcept C197341189 @default.
- W2105184098 hasConcept C2776914184 @default.
- W2105184098 hasConcept C2778399782 @default.
- W2105184098 hasConcept C2779830541 @default.
- W2105184098 hasConcept C2908647359 @default.
- W2105184098 hasConcept C41008148 @default.
- W2105184098 hasConcept C50644808 @default.
- W2105184098 hasConcept C6557445 @default.
- W2105184098 hasConcept C71924100 @default.
- W2105184098 hasConcept C86803240 @default.
- W2105184098 hasConcept C99454951 @default.
- W2105184098 hasConceptScore W2105184098C108010975 @default.
- W2105184098 hasConceptScore W2105184098C118403218 @default.
- W2105184098 hasConceptScore W2105184098C119857082 @default.
- W2105184098 hasConceptScore W2105184098C126322002 @default.
- W2105184098 hasConceptScore W2105184098C154945302 @default.
- W2105184098 hasConceptScore W2105184098C169760540 @default.
- W2105184098 hasConceptScore W2105184098C170493617 @default.
- W2105184098 hasConceptScore W2105184098C197341189 @default.
- W2105184098 hasConceptScore W2105184098C2776914184 @default.
- W2105184098 hasConceptScore W2105184098C2778399782 @default.
- W2105184098 hasConceptScore W2105184098C2779830541 @default.
- W2105184098 hasConceptScore W2105184098C2908647359 @default.
- W2105184098 hasConceptScore W2105184098C41008148 @default.
- W2105184098 hasConceptScore W2105184098C50644808 @default.
- W2105184098 hasConceptScore W2105184098C6557445 @default.
- W2105184098 hasConceptScore W2105184098C71924100 @default.
- W2105184098 hasConceptScore W2105184098C86803240 @default.
- W2105184098 hasConceptScore W2105184098C99454951 @default.
- W2105184098 hasIssue "4" @default.
- W2105184098 hasLocation W21051840981 @default.
- W2105184098 hasLocation W21051840982 @default.
- W2105184098 hasLocation W21051840983 @default.
- W2105184098 hasLocation W21051840984 @default.
- W2105184098 hasOpenAccess W2105184098 @default.
- W2105184098 hasPrimaryLocation W21051840981 @default.
- W2105184098 hasRelatedWork W1904307646 @default.
- W2105184098 hasRelatedWork W2043257604 @default.
- W2105184098 hasRelatedWork W2105184098 @default.
- W2105184098 hasRelatedWork W2133167386 @default.
- W2105184098 hasRelatedWork W2170112692 @default.
- W2105184098 hasRelatedWork W2524912940 @default.
- W2105184098 hasRelatedWork W3106871688 @default.
- W2105184098 hasRelatedWork W3130786427 @default.
- W2105184098 hasRelatedWork W3199494145 @default.
- W2105184098 hasRelatedWork W3207964041 @default.
- W2105184098 hasVolume "72" @default.
- W2105184098 isParatext "false" @default.
- W2105184098 isRetracted "false" @default.
- W2105184098 magId "2105184098" @default.
- W2105184098 workType "article" @default.