FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2105203702> ?p ?o ?g. }

• W2105203702 endingPage "174" @default.
• W2105203702 startingPage "171" @default.
• W2105203702 abstract "Extreme neonatal jaundice occurs infrequently but carries a high risk of permanent sequelae (kernicterus) when it does. Rapid therapeutic intervention has the potential to reduce this risk in some infants. Several case reports of infants with acute intermediate to advanced bilirubin encephalopathy shows that reversal may be possible. Phototherapy can be instituted at the flip of a switch, whereas other therapeutic measures necessarily involve delays. Therefore, high-intensity phototherapy must be regarded as an emergency measure in infants presenting with extreme jaundice and even more so in the presence of neurological symptoms. The principal and well-described effect of phototherapy involves conversion of bilirubin IXα (z, z) to more polar isomers, which are excreted in bile and urine. When care is taken to maximize the spectral power of phototherapy lights, and whenever possible with measures added to reduce the enterohepatic circulation of bilirubin, very rapid reductions in total serum bilirubin levels are possible. A hypothesis has been advanced that conversion of bilirubin to more polar photoisomers, which can reach relative concentrations of 20%-25% of total serum bilirubin within 1-2 hours, might have a direct neuroprotective effect. This theory posits that because polar molecules generally require a transporter to cross the blood-brain barrier, bilirubin photoisomers should be less prone to enter the brain. Although this theory has some support in in vitro toxicity studies, the evidence is controversial. Until further experimental support can be gained, photoconversion of bilirubin does not constitute a viable argument against instituting further measures against bilirubin neurotoxicity, such as intravenous immune globulin (when indicated) and exchange transfusion. Conversely, neither is the state of evidence an argument against immediate and effective phototherapy in the medical emergency of extreme neonatal jaundice." @default.
• W2105203702 created "2016-06-24" @default.
• W2105203702 creator A5063612920 @default.
• W2105203702 date "2011-06-01" @default.
• W2105203702 modified "2023-09-26" @default.
• W2105203702 title "The Role of Phototherapy in the Crash-Cart Approach to Extreme Neonatal Jaundice" @default.
• W2105203702 cites W1483217552 @default.
• W2105203702 cites W1766599144 @default.
• W2105203702 cites W1913306047 @default.
• W2105203702 cites W1927153537 @default.
• W2105203702 cites W1942778217 @default.
• W2105203702 cites W1975776648 @default.
• W2105203702 cites W1985584806 @default.
• W2105203702 cites W1986381461 @default.
• W2105203702 cites W1990692585 @default.
• W2105203702 cites W2008956909 @default.
• W2105203702 cites W2011619996 @default.
• W2105203702 cites W2019431067 @default.
• W2105203702 cites W2020318985 @default.
• W2105203702 cites W2025927505 @default.
• W2105203702 cites W2031066157 @default.
• W2105203702 cites W2031541556 @default.
• W2105203702 cites W2032568358 @default.
• W2105203702 cites W2041648302 @default.
• W2105203702 cites W2046691502 @default.
• W2105203702 cites W2082982868 @default.
• W2105203702 cites W2085110538 @default.
• W2105203702 cites W2088169858 @default.
• W2105203702 cites W2088971389 @default.
• W2105203702 cites W2089784264 @default.
• W2105203702 cites W2090073052 @default.
• W2105203702 cites W2099404361 @default.
• W2105203702 cites W2115666495 @default.
• W2105203702 cites W2117522152 @default.
• W2105203702 cites W2117880641 @default.
• W2105203702 cites W2131843383 @default.
• W2105203702 cites W2135956314 @default.
• W2105203702 cites W2152139714 @default.
• W2105203702 cites W2166643235 @default.
• W2105203702 cites W2168354723 @default.
• W2105203702 cites W2169478822 @default.
• W2105203702 cites W2186384613 @default.
• W2105203702 cites W4206399510 @default.
• W2105203702 cites W4212973375 @default.
• W2105203702 cites W4236856093 @default.
• W2105203702 cites W4247301755 @default.
• W2105203702 cites W4253936166 @default.
• W2105203702 cites W4256576165 @default.
• W2105203702 doi "https://doi.org/10.1053/j.semperi.2011.02.012" @default.
• W2105203702 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21641491" @default.
• W2105203702 hasPublicationYear "2011" @default.
• W2105203702 type Work @default.
• W2105203702 sameAs 2105203702 @default.
• W2105203702 citedByCount "27" @default.
• W2105203702 countsByYear W21052037022012 @default.
• W2105203702 countsByYear W21052037022013 @default.
• W2105203702 countsByYear W21052037022014 @default.
• W2105203702 countsByYear W21052037022015 @default.
• W2105203702 countsByYear W21052037022016 @default.
• W2105203702 countsByYear W21052037022017 @default.
• W2105203702 countsByYear W21052037022018 @default.
• W2105203702 countsByYear W21052037022019 @default.
• W2105203702 countsByYear W21052037022020 @default.
• W2105203702 countsByYear W21052037022021 @default.
• W2105203702 countsByYear W21052037022022 @default.
• W2105203702 crossrefType "journal-article" @default.
• W2105203702 hasAuthorship W2105203702A5063612920 @default.
• W2105203702 hasConcept C126322002 @default.
• W2105203702 hasConcept C181199279 @default.
• W2105203702 hasConcept C185592680 @default.
• W2105203702 hasConcept C187212893 @default.
• W2105203702 hasConcept C2776217839 @default.
• W2105203702 hasConcept C2776253728 @default.
• W2105203702 hasConcept C2777513400 @default.
• W2105203702 hasConcept C2778083895 @default.
• W2105203702 hasConcept C2778456037 @default.
• W2105203702 hasConcept C2778620825 @default.
• W2105203702 hasConcept C2779219270 @default.
• W2105203702 hasConcept C55493867 @default.
• W2105203702 hasConcept C62231903 @default.
• W2105203702 hasConcept C71924100 @default.
• W2105203702 hasConceptScore W2105203702C126322002 @default.
• W2105203702 hasConceptScore W2105203702C181199279 @default.
• W2105203702 hasConceptScore W2105203702C185592680 @default.
• W2105203702 hasConceptScore W2105203702C187212893 @default.
• W2105203702 hasConceptScore W2105203702C2776217839 @default.
• W2105203702 hasConceptScore W2105203702C2776253728 @default.
• W2105203702 hasConceptScore W2105203702C2777513400 @default.
• W2105203702 hasConceptScore W2105203702C2778083895 @default.
• W2105203702 hasConceptScore W2105203702C2778456037 @default.
• W2105203702 hasConceptScore W2105203702C2778620825 @default.
• W2105203702 hasConceptScore W2105203702C2779219270 @default.
• W2105203702 hasConceptScore W2105203702C55493867 @default.
• W2105203702 hasConceptScore W2105203702C62231903 @default.
• W2105203702 hasConceptScore W2105203702C71924100 @default.
• W2105203702 hasIssue "3" @default.
• W2105203702 hasLocation W21052037021 @default.
• W2105203702 hasLocation W21052037022 @default.

• next