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• W2105256531 abstract "The effect of Pentylenetetrazol (PTZ, Metrazol) upon the identified neurons of Japanese land snail was studied.1) In the pleuro-parieto-visceral ganglion of Japanese land snail, Euhadra peliomphala, three types of cells can be differentiated morphologically and functionally as those; depolarized by acetylcholine (D-cell), hyperpolarized by acetylcholine (H-cell) and indifferent to acetylcholine (I-cell).2) PTZ produces a phasic depolarization followed by a sustained depolarization in the D- and H-cells.3) PTZ has no specific effect upon the I-cell.4) By application of d-tubocurarine, atropine and hexamethonium, the typical phasic activity evoked by PTZ is not affected in either the D- or H-cells, suggesting that the effect of PTZ is not of synaptic origin but of endogeneous origin.5) Neither cholinergic nor noncholinergic inhibitory input to the Dand H-cells are affected even at the peak of PTZ activity." @default.
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• W2105256531 date "1973-01-01" @default.
• W2105256531 modified "2023-10-16" @default.
• W2105256531 title "PENTYLENETETRAZOL-INDUCED INTRACELLULAR POTENTIAL CHANGES OF THE NEURON OF THE JAPANESE LAND SNAIL EUHADRA PELIOMPHALA" @default.
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• W2105256531 doi "https://doi.org/10.2170/jjphysiol.23.261" @default.
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